iosr-JDMS   Volume-24 ~ Issue-6 ~ June 2025

Abstract: Introduction: COVID 19 is new pandemic disease .it mainly affects respiratory system but can affect many other system in human body. Gastrointestinal system has been found to be affected in many patients. Gastrointestinal (GI) symptoms were very common in patients with coronavirus disease 2019 (COVID-19). It is unclear if the presence of GI symptoms is associated with poor outcomes in COVID-19. We aim to assess GI symptoms and their outcome and severity in covid 19 patients. it could be used for prognostication in hospitalized patients with COVID-19.......

Keywords- COVID-19, Gastrointestinal manifestations, Severe-acute-respiratory-syndrome coronavirus, Outcomes· Mortality· Length of stay

[1] Santarpia JL, Rivera DN, Herrera V, Morwitzer MJ, Creager H, Santarpia GW, Et Al. Transmission Potential Of SARS-Cov-2 In Viral Shedding Observed At The University Of Nebraska Medical Center
[2] Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, Et Al. Clinical Features Of Patients Infected With 2019 Novel Coronavirus In Wuhan, China. Lancet. 2020 Feb 15;395(10223):497–506. .
[3] Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, Et Al. Clinical Characteristics Of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia In Wuhan, China. JAMA. 2020 Feb 7;323(11):1061–9.
[4] Aloysius M, Thatti A, Gupta A. COVID-19 Presenting As Acute Pancreatitis. Pancreatology. 2020;S1424–3903(20):30154.
[5] Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, Et Al. Clinical Characteristics Of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia In Wuhan, China. JAMA. 2020 Feb 7;323(11):1061–9.

Abstract: Background: Chronic liver disease (CLD) is a progressive deterioration of liver functions for more than six months, which includes synthesis of clotting factors, other proteins, detoxification of harmful products of metabolism, and excretion of bile. CLD is a continuous process of inflammation, destruction, and regeneration of liver parenchyma, which leads to fibrosis and cirrhosis. For predicting prognosis of end-stage liver disease and severity, various prognostic models are...

[1] Cirillo P, Sato W, Reungjui S, Heinig M, Gersch M, Sautin Y, Et Al. Uric Acid, The Metabolic Syndrome, And Renal Disease. J Am Soc Nephrol. 2006 Dec;17(12 Suppl 3):S165-168
[2] Noklang S, Noklang I, Chirumamilla SSK, Kannauje PK. Serum Uric Acid Level In Chronic Liver Disease And Its Correlation With Child–Pugh Score In A Tertiary Care Hospital From South India. J Family Med Prim Care [Internet]. 2023 Nov [Cited 2024 Jun 22];12(11):2696–701. Available From: Https://Www.Ncbi.Nlm.Nih.Gov/Pmc/Articles/PMC10771220/ [1] Penman ID, Ralston S, Strachan MWJ, Hobson RP, Editors. Davidson’s Principles And Practice Of Medicine. 24th Edition. [Edinburgh]: Elsevier; 2023.
[3] Yadav NA, Pradeep C, Handral MS. Predictive Ability Of Serum Uric Acid Levels In Assessing The Severity Of Chronic Liver Disease. Int J Sci Stud 2023;10(10):57-62.
[4] Noklang S, Noklang I, Chirumamilla SS, Kannauje PK. Serum Uric Acid Level In Chronic Liver Disease And Its Correlation With Child–Pugh Score In A Tertiary Care Hospital From South India. J Family Med Prim Care 2023;12:2696‐701.
[5] Gupta PK, Agarwal H, Singhal S, Manocha K. Study Of Association Between Serum Uric Acid Levels And Chronic Liver Disease. Eur J Mol Clin Med 2021;8:1169-73.

Abstract: Introduction: Renal sinus lesions are a diagnostic challenge due to overlapping imaging features of renal pelvis strictures and parapelvic cysts. Differentiating them is important, as they have various clinical implications and management. Strictures cause obstructive uropathy. Parapelvic cysts are usually benign, non-communicating fluid collections that can mimic obstruction on imaging. Aim: To evaluate and differentiate renal pelvis strictures from parapelvic cysts using ultrasound, computed tomography (CT), and magnetic resonance urography.......

Keywords: Parapelvic cyst, Renal Pelvis, Pelviureteric junction, Obstruction, Imaging features, Strictures

[1] O’Neill WC. Sonographic Evaluation Of Renal Failure. Am J Kidney Dis. 2000;35(6):1021–1038.
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[4] Smith RC, Verga M, Mccarthy S, Rosenfield AT. Diagnosis Of Acute Flank Pain: Value Of Unenhanced Helical CT. AJR Am J Roentgenol. 1996;166(1):97–101.
[5] Kawashima A, Sandler CM, Ernst RD, Et Al. Imaging Of Renal Trauma: A Comprehensive Review. Radiographics. 2001;21(3):557–574..

Abstract: Christ-Siemens-Touraine syndrome (CST syndrome), also known as Anhidrotic Ectodermal Dysplasia (AED) or Hypohidrotic Ectodermal Dysplasia (HED), is the most common form of ectodermal dysplasia (ED). It is a congenital and hereditary condition caused by mutations in the genes of the ectodysplasin/NF-kappa B signaling pathway, which are necessary for the proper development of several ectodermal structures including teeth, nails.......

Keywords : Anodontia, Oligodontia, Anhidrotic Ectodermal Dysplasia (AED), Dental management, Pediatric dentistry.

[1] Schnabl D, Grunert I, Schmuth M,Kapferer-Seebacher I. Prosthetic Rehabilitation Of Patients With Hypohidrotic Ectodermal Dysplasia: A Systematic Review. J Oral Rehabil. 2018;45:555–570. Https://Doi.Org/10.1111/Joor.12638
[2] Anbouba GM, Carmany EP, Natoli JL. The Characterization Of Hypodontia, Hypohidrosis, And Hypotrichosis Associated With X-Linked Hypohidrotic Ectodermal Dysplasia: A Systematic Review. Am J Med Genet Part A. 2020;1–11.
Https://Doi.Org/10.1002/Ajmg.A.61493.
[3] Bashyam MD, Chaudhary AK, Reddy EC, Reddy V, Acharya V, Nagarajaram HA, Devi AR, Bashyam L, Dalal AB, Gupta N, Kabra M, Agarwal M, Phadke SR, Tainwala R, Kumar R, Hariharan SV. A Founder Ectodysplasin A Receptor (EDAR) Mutation Results In A High Frequency Of The Autosomal Recessive Form Of Hypohidrotic Ectodermal Dysplasia In India. Br J Dermatol. 2012 Apr;166(4):819-29. Doi: 10.1111/J.1365-2133.2011.10707.X. Epub 2012 Mar 5. PMID: 22032522.
[4] Cluzeau C, Hadj-Rabia S, Jambou M, Mansour S, Guigue P, Masmoudi S, Bal E, Chassaing N, Vincent MC, Viot G, Clauss F, Manière MC, Toupenay S, Le Merrer M, Lyonnet S, Cormier-Daire V, Amiel J, Faivre L, De Prost Y, Munnich A, Bonnefont JP, Bodemer C, Smahi A. Only Four Genes (EDA1, EDAR, EDARADD, And WNT10A) Account For 90% Of Hypohidrotic/Anhidrotic Ectodermal Dysplasia Cases. Hum Mutat. 2011 Jan;32(1):70-2. Doi: 10.1002/Humu.21384. PMID: 20979233.

Abstract: Background: Locally advanced breast cancer (LABC) remains a significant clinical burden, especially in low- and middle-income countries where late presentation is common. Neoadjuvant chemotherapy (NACT) is a key component of treatment, aimed at tumor downstaging and improving surgical outcomes. This study evaluates the clinical and pathological response to NACT in LABC, along with associated toxicities. Materials and Methods: This prospective observational study was conducted at Assam Medical College and Hospital over a one-year period, including 40 female patients with histologically confirmed LABC. Patients received either the ACT.........

Keywords: Locally advanced breast cancer, Neoadjuvant chemotherapy, Clinical response, Pathological response, Chemotherapy toxicity

[1] Zhang S, Jin Z, Bao L, Shu P. The Global Burden Of Breast Cancer In Women From 1990 To 2030: Assessment And Projection Based On The Global Burden Of Disease Study 2019. Front Oncol. 2024;14:1364397.
[2] Mehrotra R, Yadav K. Breast Cancer In India: Present Scenario And The Challenges Ahead. World J Clin Oncol. 2022;13(3):209-18.
[3] Tartar M, Comstock CE, Kipper MS. Locally Advanced Breast Cancer (LABC) And Neoadjuvant Chemotherapy. Breast Cancer Imaging. Philadelphia: Mosby; 2008. P. 224-301.
[4] Garg PK, Prakash G. Current Definition Of Locally Advanced Breast Cancer. Curr Oncol. 2015;22(5):E409-10.
[5] Moneer M, El-Didi M, Khaled H. Breast Conservative Surgery: Is It Appropriate For Locally Advanced Breast Cancer Following Downstaging By Neoadjuvant Chemotherapy? A Pathological Assessment. Breast. 1999;8(6):315-9..

Abstract: Background: Portal hypertension is a routinely observed clinical condition that develops due to various hepatic and extrahepatic conditions. The main objective of this study is to assess the hepatic parenchyma and spectrum of vascular hemodynamic changes in patients with portal hypertension using Duplex ultrasonography before and after beta blocker (i.e. Propranolol). Ultrasonography plays an important role in the diagnosis and follows up of Portal hypertension patients. Materials and Methods: In this.........

Keywords: Portal hypertension, Ultrasound, Color Doppler study, Propranolol.

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[2]. Colli A, Cocciolo M, Riva C, Et Al. Abnormalities Of Doppler Waveform Of The Hepatic Veins In Patients With Chronic Liver Disease: Correlation With Histologic Findings. AJR Am J Roentgenol 1994;162:833–837.
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[5]. Baik SK, Kim JW, Kim HS, Kwon SO, Kim YJ, Park JW, Et Al. Recent Variceal Bleeding: Doppler US Hepatic Vein Waveform In Assessment Of Severity Of Portal Hypertension And Vasoactive Drug Response. Radiology. 2006 Aug;240(2):574–80

Abstract: Liver abscess is collection of pus in the liver parenchyma. It can be amoebic or pyogenic. Amoebic liver abscess (ALA) is the most commonly seen extra intestinal manifestation of Entamoeba infection.[1] The presentation includes wide spectrum depicting pathology from asymptomatic carrier state to dysentery to fulminant colitis or liver abscess and colonic perforation. The trophozoites penetrate the intestinal mucosal layer causing amoebic colitis which is carried along the portal circulation to produce liver abscess and this abscess may rupture into peritoneal, pericardial........

[1] Stanley Sl Jr. Amoebiasis. Lancet. 2003;361(9362):1025–1034.
[2] Haque R, Huston Cd, Hughes M, Houpt E, Petri Wa Jr. Amebiasis. N Engl J Med. 2003;348(16):1565–1573.
[3] Shirley Da, Moonah Sn, Petri Wa Jr. Entamoeba Histolytica Infection. Nat Rev Dis Primers. 2019;5(1):49.
[4] World ealth Singh A, Kaur M, Singh S. Amoebic Perforation Of The Cecum: A Rare Complication. Indian J Surg. 2010;72(6):481-483..

Abstract: Rationale: This case report showcases an incidence of Ossifying Fibroma of hard palate which is extremely rare and to consider in the differential diagnosis of the mesenchymal tumours of oral cavity. Patient concern: 44 years old female patient reported to our department with a complaint of swelling in the anterior hard palate for the past 4 months associated with discomfort.......

Key words: Ossifying Fibroma , hard palate , mesenchymal tumour, case report

[1] Iwase M, Saida N, Tanaka Y. Fibrolipoma Of The Buccal Mucosa: A Case Report And Review Of The Literature. Case Reports In Pathology. 2016;2016(1):5060964.
[2] Acath D, Naik P, Mukherjee J. Oral Fibrolipoma. J. Contemp. Dent. 2013 Jan;3(1):49-51.
[3] Vadvadgi VH, Saini R. Oral Fibrolipoma Of The Oral Cavity. Int J Exp Dent Sci. 2014 Jul 1;3:106-8.
[4] Tandon A, Srivastava A, Jaiswal R, Gaur A. Oral Fibrolipoma: A Rare Clinicopathological Entity. Journal Of Oral And Maxillofacial Pathology. 2023 Jul 1;27(3):537-9.
[5] Keerthana DR, Angadi PV. Fibrolipoma Of The Buccal Mucosa: A Rare Case Report. Indian Journal Of Health Sciences And Biomedical Research Kleu. 2023 Jan 1;16(1):171-4.

Abstract: Background: The effectiveness of complete dentures diminishes over time due to alveolar ridge resorption, mucosal changes, and wear of denture materials. These changes lead to loss of retention, stability, and patient comfort, necessitating corrective measures. Denture relining serves as conservative alternatives to full denture replacement, aiming to restore fit and function while preserving occlusal relationships and esthetics.
Materials and Methods: This literature-.........

Keywords: Complete dentures, Denture relining, Occlusal stability, Ridge resorption, Impression materials, Soft liners, Prosthodontic rehabilitation.

[1] Jemli, Safa. "Rebasing As A Problem-Solving In Complete Dentures." Saudi J Oral Dent Res 6.6 (2021): 227-233.
[2] Christensen, Finn Tengs. "Relining Techniques For Complete Dentures." The Journal Of Prosthetic Dentistry 26.4 (1971): 373-381.
[3] Buchman, Jack. "Relining Full Upper And Lower Dentures." The Journal Of Prosthetic Dentistry 2.5 (1952): 703-710.
[4] Gillis, Robert R. "A Relining Technique For Mandibular Dentures." The Journal Of Prosthetic Dentistry 10.3 (1960): 405-410.
[5] Smith, Dale E., James L. Lord, And Charles L. Bolender. "Complete Denture Relines With Autopolymerizing Acrylic Resin Processed In Water Under Air Pressure." The Journal Of Prosthetic Dentistry 18.2 (1967): 103-115..

Abstract: Introduction. Based on Ministry of Health Constitution Law Number 36 of 2009 concerning Health, Community Health Centers called as community health centers are first-level health services facilities that organized and promotive, preventive, curative, rehabilitative and palliative health services by prioritizing promotive and preventive in their working areas. Aim of the study. The aim of this study was.......

Keywords: The patient’s need, availability of dental treatment, Comunity Health Center

[1] Regulation Of The Minister Of Health Of The Republic Of Indonesia Number 43 Of 2019. Public Health Center
[2] Yamini EA., Analysis Of Factors Influencing Consumers In Choosing A Hospital In Jpogyakarta City. Management Insight: Scientific Journal Of Management. 2022; 17(1):131-140
[3] Yu E., Li M., Xue And Zhang L. Patient Preference And Choice Of Healthcare Providers In Shanghai, China. A Cross-Sectional Study. BMJ. 2017;7(10):1-16
[4] Ministry Of Health Of The Republic Of Indonesia. Law Of The Republic Of Indonesia Number 36 Of 2009 Concerning Health. Jakarta: Ministry Of Health Of The Republic Of Indonesia: 2009.
[5] Stephens MB, Wiedemer JP, Kushner GM. Dental Problems In Primary Care. Am Fam Phys, 2018. 98(11): 654-660.

Abstract: Background: The human foot possesses a special intricate mechanism responsible for bipedal gait. The plantar arches of the foot are the most distinctive feature of a human being which can be normal, high arch or low arch. Materials and Methods: A cross-sectional study was conducted on 398 subjects (164 males and 234 females) in the Department of Anatomy, RIMS, Imphal from May 2023 to November 2023.Staheli’s Index was used for classification of foot arches. Results: The mean value.......

Keywords: BMI, Staheli Index, Arches of foot

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[2] Mehta, Suri. Snell’s Clinical Anatomy By Regions.South Asian Ed. New Delhi: Wolters;2020.P.578-580
[3] Koshi. Cunningham’s Manual Of Practical Anatomy.16th Ed.USA:Oxford;2017.P. 273
[4] Anthony V D’ Antoni . Arches Of Foot.Standring S,Editor. Gray’s Anatomy:The Anatomical Basis Of Clinical Practice.42nd Ed. London: Elsevier;2021.P.1454-1455
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Abstract: Background: Periodontal regeneration remains a clinical challenge, especially in cases involving intrabony defects. Emdogain, an enamel matrix derivative, has shown promise in promoting the regeneration of periodontal tissues. This study aimed to evaluate the clinical effectiveness of Emdogain in periodontal regeneration over a 6-month period. Materials and Methods:
A total of 40 systemically.......

Keywords: Clinical trial, Enamel matrix derivative, Emdogain, Intrabony defects, Periodontal regeneration, Randomized controlled trial

[1] Youssef AR, Emara R, Taher MM, Al-Allaf FA, Almalki M, Almasri MA, Siddiqui SS. Effects Of Mineral Trioxide Aggregate, Calcium Hydroxide, Biodentine And Emdogain On Osteogenesis, Odontogenesis, Angiogenesis And Cell Viability Of Dental Pulp Stem Cells. BMC Oral Health. 2019; 19(1):133.
[2] Greenstein G. Emdogain: Evidence Of Efficacy. Compend Contin Educ Dent. 2000; 21(4):299–305, 308, 310 Passim; Quiz 314.
[3] Dobbs WE. EMDOGAIN. Northwest Dent. 1999; 78(5):27–9.
[4] Mohamed RN, Basha S, Al-Thomali Y, Tawfik Enan E. Enamel Matrix Derivative (Emdogain) In Treatment Of Replanted Teeth: A Systematic Review. Acta Odontol Scand. 2019; 77(3):168–72.
[5] Gestrelius S, Lyngstadaas SP, Hammarström L. Emdogain—Periodontal Regeneration Based On Biomimicry. Clin Oral Investig. 2000; 4(2):120–5.

Abstract: Acute pancreatitis typically manifests as epigastric pain accompanied by elevated serum pancreatic enzymes. It exhibits a wide clinical and radiological spectrum, ranging from mild interstitial or oedematous inflammation to severe necrotizing forms accompanied by substantial local and systemic complications. Acute pancreatitis is a potentially lethal disease in certain circumstances, so early detection and severity assessment are necessary to prevent complications and reduce mortality. Computed tomography......

[1] Mortele KJ, Mergo PJ, Taylor HM, Et Al. Peripancreaticvascular Abnormalities Complicating Acute Pancreatitis: Contrast-Enhanced Helical CT Findings. Eur J Radiol.2004;52(1):67–72.
[2] Mortele KJ1, Wiesner W, Intriere L, Shankar S:A Modifiedct Severity Index For Evaluating Acute Pancreatitis: Improvedcorrelation With Patient Outcome.AJR 2004 Nov;183(5):1261-5.
[3] Balthazar EJ. Acute Pancreatitis: Assessment Of Severity Withclinical And CT Evaluation. Radiology. 2002;223(3):603–13.
[4] Banks PA, Bollen TL, Dervenis C, Gooszen HG, Johnson CD, Sarr MG, Et Al. Classification Of Acute Pancreatitis—2012: Revision Of The Atlanta Classification And Definitions By International Consensus. Gut. 2013;62(1):102–11.
[5] Lankisch PG, Warnecke B, Bruns D, Et Al. The APACHE II Score Is Unreliable To Diagnose Necrotizing Pancreatitis On Admission To Hospital. Pancreas 2002; 24:217–222