Abstract: Although curcumin (Cur)has a variety of pharmacological effects, its defects including low solubility, poor stability and low bioavailability, greatly limit its use in food and pharmaceutical products. In this work, we successfully encapsulated Cur in liposomes and the optimal amount of Cur, lecithin, and cholesterol was 2, 80, and 20 mg, respectively. The EE of the prepared liposomes was 95%, the particle size was about200 nm and zeta potential was -27.5mV. This work may provide a theoretical guidance forthe extensive and mature application of Cur.
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