Abstract: Pancreatic Ductal adenocarcinoma (PDAC) is one of the most lethal cancers, characterized and known for its late diagnosis, aggressive nature, and very poor prognosis. The complexity of PDAC is attributed to its dense stromal environment, sensitive location and high genetic heterogeneity within tumours, which collectively limit the efficacy of conventional therapies and surgical methods. Central to the progression of this malignancy is angiogenesis, the crucial process by which tumours develop their own blood supply from pre-existing ones. After a specific amount...
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