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Abstract: We propose some novel tools to combat the long existing problem of inter-galactic parasites such as Klaousmodiumcruzi which are known to have caused havoc amongst various populations. We present solution after attentively observing various scientific procedures undertaken by the greatest scientists of our times who existed in segmented Claymation. In total we have investigated 31 different experiments and propose this ground-breaking quick fix which will truly transform the field. We'd also like to boast that our work has received accolades from the scientists whose work we followed including the greats like R'onaldI'saac and Charles Kao.
Keywords: K.cruzi, Parasites, Therapy, Drug Delivery
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[3]. Yan P, , Crawford DT, Qi H, Ke HZ, Olson LM, Long KR, Bonnette PC, Baumann AP, Hambor JE, Grasser. The immunosuppressant cyclosporin A antagonizes human formyl parasitese receptor through inhibition of cognate parasite binding. J. Immunol. 2006;177:7050–7058.
[4]. Buckbinder L, Crawford DT, Qi H, Ke HZ, Olson LM, Long KR, Bonnette PC, Baumann AP, Hambor JE, Grasser WA, Pan LC, Owen TA, Luzzio MJ, Hulford CA, Gebhard DF, Paralkar VM, Simmons HA, Kath JC, Roberts WG, Smock SL, Guzman-Perez A, Brown TA, Li M. Proline-rich tyrosine kinase 2 regulates osteoprogenitor cells and bone formation and offers an anabolic treatment approach for osteoporosis. Proc. Natl. Acad. Sci. USA. 2007;104(25):10619–10624.
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Abstract: Le neuroblastome ou sympathoblastome est une tumeur maligne de type embryonnaire, qui appartient au groupe de tumeurs de la crête neurale, il constitue la troisième cause de cancers chez l'enfant. 90% des neuroblastomes surviennent avant l'âge de 10 ans dont plus de 50 % sont métastatiques au moment du diagnostic [1], cependant les métastases orbitaires sont relativement rares. Il y a peu de travaux publiés détaillant les manifestations orbitaires etophtalmiques du neuroblastome. Nous rapportons ici un cas d'un nourrisson ayant présenté initialement une exophtalmie unilatérale droite dont l'exploration a révélé un neuroblastome surrénalien.......
[1]. Ahmed S, Goel S, Khandwala M, Agrawal A, Chang B, Simmons IG. Neuroblastomawith orbital metastsis:
[2]. ophthalmic presentation and role of ophthalmologists. Eye 2006; 20: 466-470.
[3]. Rubie H. Neuroblastome. EncyclMédChir (Editions Scientifiques et Médicales Elsevier SAS), Pédiatrie, 4-100-E-80, 2001, 12 p.
[4]. Les tumeurs du système nerveux sympathique : Le Neuroblastome. BERNARD. JL. [Site Internet].24 décembre 2009 25 novembre 1998. URL :http://www.rheop.org/Le-Neuroblastome.
[5]. West S, Correa JD, Germain M, Balsam D, Rosen J. Neuroblastoma 2005; emedicine.com/radio/topic472. Htm..
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Abstract: In this research, a new nano graphene oxide based solid phase extraction followed by Dispersive Liquid-Liquid Microextraction was applied as simple, rapid and sensitive determination of trace amounts of Propranolol(PRO) in urine samples with HPLC-UVD. Several factors influencing the extraction of PRO, such as pH, adsorbent amounts, extraction time, organic solvent type and the composition of solvent and desorption conditions were studied and optimized. Under optimum condition, the limit of detection (LOD) and limit of quantification (LOQ) of the proposed method were 2 ng mL−1and 6.6 ng/mL, respectively. Good linear behaviour over the investigated concentration ranges (2-2000 ng mL-1) and good correlation coefficient of 0.9901(r2) were obtained. The relative standard deviations (RSDs) based on three determinations at 2, 20, 200 ng ml-1 levels of PRO was less than 9.7 %.The findings of the present study may provide clinical and diagnostic laboratories.
Keywords: Propranolol (PRO);Nano Grapheme oxide(NGO);Solid Phase Extraction(SPE);High Performance Liquid Chromatography(HPLC); Dispersive Liquid-Liquid microextraction(DLLME); Urine analysis
[1]. C.Jantarat, N.Tangthong, S.Songkro,G.P. Martin, R.Suedee, S-Propranolol imprinted polymer nanoparticle-on-microsphere composite porous cellulose membrane for the enantioselectively controlled delivery of racemic propranolol, International Journal of Pharmaceutics 349 (2008) 212–225.
[2]. G.G. Oliveira, D.C. Azzi, F.C. Vicentini, E.R. Sartori, O.F. Filho, Voltammetric determination of verapamil and propranolol using a glassy carbon electrode modified with functionalized multiwalled carbon nanotubes within a poly (allylamine hydrochloride) film, J. Electroanal. Chem. 708 (2013) 73–79.
[3]. J. Zhanga, L. Dinga, A. Wenb, F. Wua, L. Suna, L. Yang, An HPLC–ESI–MS method for the determination of propranolol in human plasma and its application to pharmacokinetic studies, Asian J. Pharm. Sci. 4 (2009) 169–177.
[4]. T. Alizadeh, L. Allahyari, Highly-selective determination ofcarcinogenic derivative of propranolol by using a carbon paste electrode incorporated with nano-sized propranolol-imprinted polymer, Electrochim. Acta 111 (2013) 663–673.
[5]. K. Scida, P.W. Stege, G. Haby, G.A. Messina, C.D. García, Recent applications of carbon-based nanomaterials in analytical chemistry: critical review, Anal.Chim. Acta 691 (2011) 6–7...
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Paper Type | : | Research Paper |
Title | : | Algorithms for Search for Common Ancestors |
Country | : | |
Authors | : | Rita Gitik |
: | 10.9790/3008-1305011622 |
Abstract: Generation theory was developed as a tool for studying self-reproducing systems. In this paper we show that this theory can be applied to a search for common ancestors of living organisms. We give two algorithms with flowcharts in pseudocode for finding common ancestors of a set of microbes and describe the connections with the genography problem.
Keywords: Algorithm, Flowchart, Microbe, DNA, Graph
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[3]. R. Gitik, Optimal Seeding and Self-Reproduction from a Mathematical Point of View, J. of Computer Engineering, IOSR, September – October 2016, 18, Issue 5, Version 5, pp. 56-59.
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[5]. Y. Haile-Selassie et al, New Species from Ethiopia Further Expands Middle Pliocene Hominin Diversity, Nature, 28 May 2015, 521, 483-488..
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Abstract: Introduction : La kératoplastie transfixiante est une intervention qui consiste à remplacer une cornée altérée de pleine épaisseur. Elle permet d'améliorer de manière importante la vision des patients ayant une malvoyance d'origine cornéenne. Elle nécessite un suivi régulier et attentif à long terme. L'Objectif de notre étude est d'évaluer les résultats anatomiques et fonctionnels des patients greffés en fonction de leur pathologie cornéenne initiale. Patients et méthodes : Il s'agit d'une étude rétrospective qui a porté sur 152 patients ayant bénéficié d'une kératoplastie transfixiante au sein du service d'ophtalmologie pédiatrique de l'hôpital 20aout de Casablanca durant une période de 8 ans..........
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206-A-10
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[5]. Qing Pan, Xiuyi Li and Yangshun Gu , Indications and outcomes of penetrating keratoplasty in a tertiary hospital in the developing
world, Clinical and Experimental Ophthalmology 2012; 40: 232–238..
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Abstract: Les paralysies oculomotrices (POM) sont fréquentes, le plus souvent acquises, responsables de diplopie et d'attitudes compensatrices de la tête. Elles sont liées à l'atteinte d'un ou de plusieurs nerfs oculomoteurs, du muscle ou encore de la plaque motrice. Si le diagnostic positif de ces affections est aisé, celles-ci posent souvent des problèmes de diagnostic étiologique, conditionnant la prise en charge thérapeutique. L'objectif de notre travail est de faire une mise au point diagnostique étiologique sur les paralysies oculomotrices périphériques. Nous rapportons une série.........
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[5]. Schields J, Schields C, Scartozzi R. Survey of 1264 patients with orbital tumors and simulating lesions. Ophthalmology 2004; 111 : 997. 100.
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Abstract: Amino quinones are used as medicines, herbicides and redox switching properties. Amino quinones are formed in the reaction of different amines with 1, 4- naphthoquinone . Synthesis of 2-amino-1, 4-napthoquinone (L1), 2-(N –acetyl) –acetamido-1, 4- naphthoquninone. (L2). 2-amino-1, 4-napthoquninoe-1 oxime (L3). and 2-(N-acetyl)-acetamido-1, 4 naphthoquinone -1, oxime (L4) were carried out. X-ray diffraction studies show that all the ligands are crystalline in nature and belong to triclinic group. Crystalline parameters and h , k, l values are calculated by using McMallie computer code. The crystalline size is determined by Scherrer formula and found to be L1 – 86.29nm, L2-57.51nm, L3 – 46.54nm and L4-34.81nm .The results are discussed in this paper.
Keywords : 2-Amino-1, 4-naphthoquinone, XRD, IR *To whom correspondence should be made
[1]. Goto, Yoshio and Tokita , Yuichi , Preparation of high- purity amino naphthoquinone with reduced amount of solvents, JPn . Kokai Tokkyo Koho JP 2008 303149A, 20081218 ( 2008).
[2]. Morimoto, Junji and Kamikawa , Takashi , Preparation of aminonapthoquinones from napthoquinones and hydroxylamines ; Jpn. Kokai Tokkyo Koho, JP 2003267938A 20030925 (2003).
[3]. Kapadia ,G J, Azuine, M.A., Balasubramanian, V., Sridhar,R, Aminonapthoquinones-a novel Class of compounds with potent antimalarial activity against plasmodium talciporum, Pharmacol.Res, 43, 363 (2001).
[4]. Sharma V. , Katoch Deepali, Soodswati, neural kumar , Bikram Singh ,Thakur Archana and Gulati Arvind ,Synthesis and Antifungal activity of 2-amino-1,4-napthoquinone using silica supported perchloric acid ( HCI04-SiO2) as a mild, recycleable and highly efficient heterogenous catalyst ,Indian J. chem, 52B,1431-1440 (2013)
[5]. Asharaf A. Aly , Esam A. Ishak, Musaed A. Alsharani, Nayef S., Al-Muaikel and Tarek M.I. Bedair, Aminonaphthoquinone in heterocyclization, Journal of Heterocyclic Chem., 49 (1) 9-20 (2012).
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Abstract: A pot experiment was carried to study the effects of N from different fertilizer on growth and yield of Indian spinach (Basella alba L.). There were six treatments comprising of control, N @ 130 kg ha-1 from urea, NH4NO3, NH4Cl, (NH4)2SO4, NaNO3. The treatments were arranged in a randomized complete block design with three replications. The results of the study indicated that addition of nitrogen from various inorganic fertilizers significantly affected the number of leaves plant-1, plant height, fresh and dry weight of leaves, stem and root. The maximum number of leaves plant-1 and the highest plant height at 45 and 60 days after sowing (DAS) were obtained with supplying nitrogen from urea whereas at 30 DAS these values were obtained with nitrogen from NaNO3. At all the growth stages, the lowest number of leaves plant-1 and the lowest plant height were observed with control........
Key words: Indian spinach, Plant heights, root, stem, urea, NH4NO3
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Abstract: The objective of the research was to record the moss species for the Cerrado phytogeographic domain of the State of Maranhão/Brazil. were identified 80 mosses species, distributed in 41 genera and 20 families. The recorded taxa, occur in almost all Brazilian phytogeographic regions. Of the analyzed families, Calymperaceae, Fissidentaceae, Sematophyllaceae and Pottiaceae were the most representative in number of specimens and species. The studied mosses have the capacity to be fixed in the most varied substrates, which facilitated the collection of a large number of briological material. The substrate most colonized was the corticolous , which proved to be the preferred for many species, followed by the terrestrial and epixylic substrates. The Cerrado of Maranhão.........
Keywords: Briological Collection , Bryology, Maranhão Plants, Mosses from Brazil.
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Abstract: The main aim and objective of the present research work was the synthesis, spectral characterization and evaluation of in vitro anticancer as well as in vivo antitumour activity of some novel oxadiazole derivatives followed by docking studies against topoisomerase I enzyme. The structural confirmations of the synthesized compounds were assigned by IR, NMR and Mass spectral analysis. Molecular docking studies were carried out by AUTO DOCK programme. The in vitro anticancer activity of the synthesized compounds (AB1-AB8) was performed by SRB assay. An investigational study was designed to evaluate the in vivo antitumor activity of synthesized compounds and study was carried out with EAC cell line induced malignant ascites on mouse tumour models. In silico molecular........
Key Words: Anticancer; molecular docking; SRB; malignant ascites and PILS etc.
[1]. Kharb R, Sharma PC, Shaharyar M. Pharmacological significance of triazole scaffold. J Enzyme Inhib Med Chem 2011; 26(1): 1-21.
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Abstract: A new series of pyrazole substituted 6-nitrobenzimidazoles have been synthesized by the oxidation of pyrazoline substituted 6-nitrobenzimidazole derivatives with iodobenzene diacetate in dichloromethane. All synthesized compounds are characterized on the basis of IR, 1H NMR and Mass spectral studies. These compounds were evaluated for anti-inflammatory activity. Results reveal that, some of the compounds exhibited good anti-inflammatory activity
Keywords: Anti-inflammatory activity, Benzimidazoles, Chalcones, Pyrazolines, Pyrazoles
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Abstract: The study on the comparative effect of different concentrations of NaCl stress on growth attributes of vegetables is an important research topic that can shed light on the impact of salt stress on plant growth and development. Salt stress is a major environmental stress that affects plant growth and yield, especially in arid and semi-arid regions where soil salinity is a common problem. In this study, different concentrations of NaCl can be applied to vegetable plants to create salt stress conditions. The growth attributes of the plants such as plant height, stem diameter, leaf area, biomass production, and yield can be measured and compared across the different NaCl concentrations. The effects of salt stress on physiological and biochemical parameters such as chlorophyll content, proline content, antioxidant activity, and ion homeostasis can also be analyzed....
Keywords: salt stress, garden pea growth , legume
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