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| Paper Type | : | Research Paper |
| Title | : | Publications Trend of Different Novel Drug Delivery Systems during 1980-2012: A Pilot Study Using Pubmed Search Tool |
| Country | : | UAE |
| Authors | : | RANA M. F. SAMMOUR || FARAH HAMAD FARAH || ALIASGHAR SHAHIWALA |
Abstract: The main objectives of this project is to explore and record the trend or pattern of scientific research articles conducted on different novel drug delivery systems, over the last 32 years (1980-2012) and try to ex-plain possible reasons that lead to such trend. Pub Med, has been used as a standard website to search for scientific articles, using different keywords related to the above mentioned topics. Published research articles on different novel drug delivery systems were recorded and analyzed to study their trends. Bar-charts showing the annual number of published articles, the total number of articles that has been published, as well as graphs showing the publications growth rates during (1980-2012), were constructed, to show the trend of such re-search.
[1]. Scheffel, U.; Rhodes, B.A.; Natarajan, T.K.; Wagner, H.N. Albumin microspheres for the study of the reticulo-endothelial system. J. Nucl. Med. 1972, 13, 498–503.
[2]. Marty, J.J.; Oppenheim, R.C.; Speiser, P. Nanoparticles: a new colloidal drug delivery systems. Pharm. ActaHelv. 1978, 53, 17–23.
[3]. A.D. Bangham, M.M. Standish, and J.C. Watkins, "Diffusion of Univalent Ions across the Lamellae of Swollen Phospholipids," J. Mol. Biol. 13, 238–252 (1965).
[4]. M. Yamada, H. Harashima, and H. Kiwada, "Kinetic Analysis of the Interaction Between Liposomes and the Complement System in Rat Serum: Re-evaluation of Size Dependency," Biol. Pharm. Bull. 21, 964–968 (1998).
[5]. Chickering DE, III, Mathiowitz E. Fundamentals of bioadhesion. In: Lehr CM, editor. Bioadhesive drug delivery systems-Fundamentals, Novel Approaches and Development. New York: Marcel Dekker; 1999. pp. 1–85.
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| Paper Type | : | Research Paper |
| Title | : | Antibiotic resistance profiles of clinical and environmental isolates of Pseudomonas aeruginosa in Calabar, Nigeria |
| Country | : | Nigeria |
| Authors | : | A-A. O. Eyo || E. O. Ibeneme || B. D. P. Thumamo || A. E. Asuquo |
Abstract: Healthcare-associated infections due to multidrug-resistant Gram-negative bacteria, including Pseudomonas aeruginosa have become increasingly difficult to treat. The hospital environments, particularly in ICUs, are common habitats for Pseudomonas aeruginosa. Spread of pathogen may occur through direct patient contact with contaminated formites and from patient-to-patient on the hands of healthcare workers. The present study was conceived to evaluate the antibiotic resistance profiles of clinical and environmental isolates of Pseudomonas aeruginosa in Calabar Metropolis.
[1]. Tacconelli, E., Cataldo, M. A., Dancer, S. J., De Angelis, G., Falcone, M., Frank, U., Kahlmeter, G., Dan, A. &Petrosillo, N. (2014). ESCMID guidelines for the management of the infection control measures to reduce transmission of multidrug resistant Gram-negative bacteria in hospitalized patients. Clinical Microbiology and Infection, 20 (1), 1 – 55.
[2]. Gooze, L. (1998). Bacterial infections associated with HIV. Retrieved July 7, 2012, from http://www.livingsite.com
[3]. Todar, K. (2008). Todar's online textbook of bacteriology. Retrieved July 5, 2013, from http://www/.textbookbacteriology.net
[4]. Rowland, B. (2009). Pseudomonas infections. Retrieved August 17, 2013, from http://www.answers.com/topic/pseudomonas-infections
[5]. Qarah, S., Cunha, B. A., Dua, P., Lessnau, K., & Madappa, T. (2009). Pseudomonas aeruginosa infections. Retrieved July 21, 2012, from http://www.emedicine.medscape.comarticle/2262748-diagnosis
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| Paper Type | : | Research Paper |
| Title | : | "Prospective Interventional Study of Avipattikar Churna in relation with AMLAPITTA vyadhi" |
| Country | : | India |
| Authors | : | Sharmili Vijay Suryavanshi |
Abstract: As incidence of the AMLAPITTA vyadhi (Hyperacidity) is increasing day by day due to the disturbed, stressful life style, Its incidence is very high and complications are also increasing we found that Avipattikar churna (powder form) used in this disease was safe, economical and easy to use with good efficacy. Therefore present study was planned to evaluate the efficacy of Avipattikar Churna on AMLAPITTA vyadhi. 30 patients were selected suffering from the AMLAPITTA vyadhi and interventional study was carried out by using the Avipattikar Churna. Churna was standardized before use.
[1]. Dr. Anna Moreshwar Kunte, Vaidya, S.S.Krushnashashtri Navare, Ashtang Hrudayam (Vagbhat),With Commentaries Of Arundatta And Hemadri ,9th Edition, Varanasi Chaukhambha Sanskrit Sanstha, 2005, Pg.No.5.
[2]. Dr, Anna Moreshwar Kunte,Vaidya ,S.S.Krushnashashtri Navare, Ashtang Hrudayam(Vagbhat),With Commentaries Of Arundatta And Hemadri, 9th Edition ,Varanasi, Chaukhambha Sanskrit Sanstha, 2005, Pg.No.23 -27.
[3]. Vaidya Jadavji Trikamji Acharya, Sushruta Samhita, Nibandhsangraha Commentary, 8th Edition, Varanasi Chaukhambha Sanskrit Sanstha, 2005 ,Pg.No 41.
[4]. Dr. Anna moreshwar kunte, Vaidya, S.S.Krushnashashtri Navarre, Ashtang Hrudayam (vagbhat), with commentaries of Arundatta and Hemadri, 9th edition, Varanasi, chaukhambha sanskrit sanstha ,2005, pg.no.6.
[5]. Dr. Anna Moreshwar Kunte,Vaidya, ,S.S.Krushnashashtri Navare, Ashtang Hrudayam (Vagbhat),With Commentaries Of Arundatta And Hemadri ,9th Edition,Varanasi, Chaukhambha Sanskrit Sanstha, 2005, Pg.No.513
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| Paper Type | : | Research Paper |
| Title | : | Prescribing Pattern of Antibiotics in Pediatric Inpatient Department of a Tertiary Care Teaching Hospital in Bangalore |
| Country | : | India |
| Authors | : | Laya Vahdati Rad || Modupalli Alekhya |
Abstract: Prescription pattern analysis oversees the observance of standards of medical treatment at all levels of the healthcare delivery system. Health professionals are primarily responsible for treatment and to know about their prescribing practices can contribute to the achievement of initiatives and regulations relevant to IUA. Evaluation of prescribing pattern will also help in minimizing adverse drug reactions as children are more susceptible to them and it shall also aid in providing cost effective medical care.The assessment of the prescription will helps to know the attitude of the physicians towards prescribing and to provide rationality in the prescription.we sought to evaluate the prescribing patterns of antibiotics in pediatric inpatient department of a tertiary care hospital.
[1]. MedicineNet[Internet].Introduction to Antibiotics. New York City: 2007 (cited Sept 28). Available from: http://www.medicinenet.com/script/main/hp.asp.
[2]. Ferris TG, Saglam D, Stafford RS, Causino N, Starfield B, Culpepper L. Changes in The daily practice of primary care for children. Arch Pediat Adole Med 1998; 3:227-233.
[3]. Bhartiy SS, Shinde M, Nandeshwar S, Tiwari SC. Pattern of prescribing practices in the Madhya Pradesh, India. Kathmandu Univ Med J 2008; 6: 55-59.
[4]. Srishyla MV, Krishnamurthy M, Naga Rani MA. Prescription audit in an Indian hospital setting using the DDD (defined daily dose) concept. Indian J Pharmacol 1994; 26:23-28.
[5]. Clinical Guidelines [Internet]. Australia: 2005 (cited Sept 30). Available from: (http://www.clinicalguidelines.gov.au/).
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| Paper Type | : | Research Paper |
| Title | : | Three New Monogenoids, From the Gills of Glassfishes (Teleostei: Perciformes: Ambassidae) Of Sharda and Ghaghra Rivers Of Tarai Region in India |
| Country | : | India |
| Authors | : | Vaishya K. || Agrawal N. |
Abstract: One new species of the monogenoidea Spicocleidus Agrawal et al., 2005 from Chanda nama (Hamilton, 1822) viz. S. brevianchoratus and two of Chandacleidus Agrawal et al., 2006 (Monogenoidea: Dactylogyridae) viz C. palliaensis and C. kheriensis are described from the gills of Pseudambassis baculis (Hamilton, 1822) = Chanda baculis collected from Pallia, and Manjhura, district Kheri (new locality record) and are described herein. The new species S. brevianchoratus characterized by 'Sickle–shaped' accessory piece, with stumpy dorsal spike and short curved shaft of ventral anchor; C. palliaensis is by dorsal bar and pointed copulatory complex; and C. kheriensis is characterized by 'V-shaped' dorsal bar and shape of anchors.
Key Words: Spicocleidus, Chandacleidus, Monogenoidean, Chanda nama, Pseudambassis baculis ,Tarai region.
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| Paper Type | : | Research Paper |
| Title | : | Molecular cloning and sequence analysis of vira-like chitinase gene from the cotton leaf worm, Spodoptera littoralis Bosid (Lepidoptera: Noctuidae), treated with two insect growth regulators |
| Country | : | Egypt |
| Authors | : | Reda F. A. Bakr || Mona F. Abd Elaziz || Nehad M, El-barky || Mohamed H. Awad || Hisham M. Abd El-Halim |
Abstract: The vira-like chitinase gene, one of the genes involved in the formation of chitin and concerned with development of insect. PCR- RFLP technique was used in the present study to compare the effect of sub-lethal doses of two IGRs, flufenoxuron (cascade) as a chitin synthesis inhibitor and tebufenozide (mimic) as a moulting hormone agonist, on this gen in Spodoptera littoralis pest. As the 2nd instar larvae were treated with sublethal doses LC25, LC50 and LC90 of the two tested IGRs. The endonucleases Spel, EcoRI and Bbsl were used to detect the molecular changes in the gene at different time intervals 6, 12, 24 and 48 hours post treatment. Bioinformatical obtained results showed significant changes in the gene sequences (mutations) of the treated groups which were dose and time dependants. For each studied group, the RNA secondary structure stems nucleotide sequences; positions and free energy were recorded.
[1]. Abo-Arab, R.B. and Salem, A. A. (2005): Efficiency of some plant extracts compare pirimiphos-methyl as insecticidal and ovicidal agents. Alex. J. Agric. Res., 50 (2): 53-60.
[2]. Anwar, E.M. and A.E.M. Abd EL-Mageed (2005). Toxicity impacts of certain insect growth regulators on some biochemical activities of the cotton leafworm. Egpt.J. Agric Res., 83 (3):1915-1935.
[3]. Bakr, R.F., El-barky, N.M., Abd Elaziz, M.F. and. Abd El-Halim, H.M (2010). Effect of Chitin synthesis inhibitors (flufenoxuron) on some biological and biochemical aspects of the cotton leaf worm Spodoptera littoralis Bosid (Lepidoptera: Noctuidae). Egypt. Acad. J. biolog. Sci., 2 (2): 43- 56.
[4]. Bakr R. F., Nehad M. El-barky, Mona F. Abd Elaziz, Mohamed H. Awad and Hisham M. E. Abd El-Halim (2014). Biological and Molecular Aspects Induced by the Insect Growth Regulator lufenuron on Spodoptera littoralis (Bosid) (Lepidoptera:Noctuidae). Egypt. Acad. J. Biolog. Sci., 6(2): 1 – 16.
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| Paper Type | : | Research Paper |
| Title | : | Floristic diversity and Phyto-sociological studies of Indrakiladri Sacred Grove in Krishna district, Andhra Pradesh, India. |
| Country | : | India |
| Authors | : | Venkatesh Rampilla || Khasim, S. Mahammad || Babu Kakumanu |
Abstract: The floristic diversity and phyto-sociological studies of the Indrakiladri sacred grove, Krishna district, Andhra Pradesh, India were investigated. More than one hectare of forest stands on four sides of the sacred grove selected and 15 sample quadrates' 1m × 1m for herbs, 5m × 5m for shrubs and 10m × 10m for trees, were laid down randomly for vegetation analysis. Floristic analysis revealed that a total of 146 species belonging to 129 genera and 47 families were observed in the sacred grove. Total number of species encountered in four sides was 115, 72, 55, and 59 in east, west, north and south side respectively. Total density of all species ranged from 50.5 plant m2 to 93.6 plant m2 and total basal area of all species between 5.13 cm2m-2 to 28.66 cm2m-2. Important value index revealed that Azadirachta indica was predominant in east side and west side, Leucaena leucocephala was dominant species in south side and north side.
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| Paper Type | : | Research Paper |
| Title | : | Green synthesis of silver nanoparticles from seed extracts of Cyperus esculentus and Butyrospermum paradoxum |
| Country | : | Nigeria |
| Authors | : | Ibironke A. Ajayi || Adewale A. Raji || Emmanuel O. Ogunkunle |
Abstract: To synthesize silver nanoparticles from two medicinally important plant seed extracts of Cyperus esculentus and Butyrospermum paradoxum for the first time and to check the potency of the crude methanolic extracts and their synthesized nanoparticles on ten different human pathogens. The percentage yields of two seed extracts were 15.10% and 18.08% respectively and subjected to phytochemical and antimicrobial screenings. For the synthesis of silver nanoparticles (AgNPs), different aqueous concentrations (1mM and 3mM) of silver nitrate solutions were prepared and added to the methanolic extracts of the two plants seeds under mild reaction conditions. Synthesis of AgNPs was confirmed from the change of colour of the reaction mixtures, change in pH, FTIR spectrum and UV-Vis study of the colloidal solutions and further subjected to antimicrobial screening.
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[2]. Armendariz V, Gardea-Torresdey JL, Jose Yacaman M, Gonzalez J, Herrera I, Parsons JG. Gold nanoparticle formation by oat and wheat biomasses. Proceedings of Conference on Application of Waste Remediation Technologies to Agricultural Contamination of Water Resources; 2002.
[3]. Song JY, Kim BS. Rapid biological synthesis of silver nanoparticles using plant leaf extracts. Bioprocess Biosyst Eng 2008; 32: 79-84.
[4]. A. J. Gavhane, P. Padmanabhan, S. P. Kamble and S. N. Jangle, Int J Pharm Bio Sci., 2012, 3(3), 88 – 100.
[5]. V. Manonmani, Vimala Juliet, International Conference on Innovation, Management and Service, IPEDR, IACSIT Press. Singapore. 14, 2011.
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| Paper Type | : | Research Paper |
| Title | : | A Study on Urinary Schistosomiasis Amongst The Inhabitants of Fufore Local Government Area of Adamawa State, Nigeria |
| Country | : | Nigeria |
| Authors | : | Ameh, V1. || Qadeer, M.A || Asher, R || Nganjiwa, J.I |
Abstract: This study was conducted to determine the prevalence of Schistosoma haematobium in Fufore Local Government Area of Adamawa State. A total of 618 samples were collected within three months, from September to November 2014 and examined for eggs of S. haematobium using the sedimentation method. Of all the samples collected 31 were infected giving an overall prevalence of 5.02%. A significant difference (p<0.05) was recorded among Gender as male have a higher chance of getting infected also a significant difference was observed among the age groups with the age group 6-15years recording the highest prevalence 4.21%. Students were found to be most affected with the disease 4.53%. Primary school students had the highest prevalence of 4.69%.Though prevalence is low, it is important to increase control measures in order eradicate the disease from this region. Routine treatment and monitoring of the infected dam is recommended so as to reduce the rate of transmission of the disease.
Key words: Adamawa State, Inhabitants, Prevalence, Urinary Schistosomiasis.
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[5]. A.A Biu, H.BKolo, and E.T, Agbadu, Prevalence of Schistosoma haematobium infection in school aged children of KondugaLocal Government Area, North Eastern Nigeria.International Journal of Biomedical and Health Sciences 5.(4), 2009 181-184.