Series-1 (May – Jun.2024)May – Jun. 2024 Issue Statistics
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Paper Type | : | Research Paper |
Title | : | Unraveling The Molecular Landscape Of Diabetic Retinopathy : Pivotal Genes And Pathways |
Country | : | India |
Authors | : | Tamil Selvan T |
: | 10.9790/ 264X-1003010107 |
Abstract: Diabetic Retinopathy (DR) is one of the major microvascular complications in diabetes mellitus and is a leading cause of vision impairment worldwide. The condition usually arise due to the chronic exposure of retinal blood capillaries to high glucose, leading to dysruption in the tight junctions of retinal capillaries, increased vascular permeability, chronic inflammation, apoptosis, and neovascularization causing vitreous heamorrhage and tractional retinal detachment followed by irreversible vision loss. Proliferative diabetic retinopathy is the advanced stage of DR and is characterized by the formation of neovessels that are immature and leaky in nature....
Keywords: Diabetic retinopathy, Neovascularization, Tractional retinal detachment, Chronic inflammation, Antioxidant defense system, Angiogenesis
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