Abstract: Background: Hemorrhoids and liver disorders related to oxidative stress are common health problems. Existing treatments are only partially effective and can sometimes be toxic. Cleome viscosa L., rich in secondary metabolites, is traditionally used for its anti-inflammatory and hepatoprotective effects. The objective of this study was to evaluate the antioxidant, anti-inflammatory, and hepatoprotective activities of the hydroalcoholic extract of Cleome viscosa in rats with induced hemorrhoids, comparing two doses (250 and 500 mg/kg) to Daflon at 10 mg/kg....
Keywords: Cleome viscosa, secondary metabolites, antioxidant, anti-inflammatory, hemorrhoids
[1]. Liang Y, Ren T, Li R, Yu Z, Wang Y, Zhang X, Qin Z, Li J, Hu J, Luo C. Natural Products With Potential Effects On Hemorrhoids: A Review. Molecules. 2024 Jun 5;29(11):2673. Doi:10.3390/Molecules29112673. PMID:38893547; PMCID:PMC11173953.
[2]. Pantalos G, Vaou N, Papachristidou S, Stavropoulou E, Tsigalou C, Voidarou C, Bezirtzoglou E. Antioxidant And Anti-Inflammatory Phytochemicals For The Treatment Of Inflammatory Bowel Disease: A Systematic Review. Appl Sci. 2024;14(5):2177. Doi:10.3390/App14052177.
[3]. Ghlichloo I, Gerriets V. Nonsteroidal Anti-Inflammatory Drugs (Nsaids). Statpearls. 2025. PMID:31613522.
[4]. British National Formulary (BNF), National Institute For Health And Care Excellence (NICE). Non-Steroidal Anti-Inflammatory Drugs. 2022.
[5]. Pacheco-Hernández B, Ayora-Talavera T, Cano-Sosa J, Noriega LG, Pacheco-López NA, Vargas-Morales JM, Medina-Vera I, Guevara-Cruz M, Chim-Aké R, Gutiérrez-Solis AL, Lugo R, Avila-Nava A. Antioxidant And Anti-Inflammatory Effects Of Traditional Medicinal Plants For Urolithiasis: A Scoping Review. Plants. 2025;14(13):2032. Doi:10.3390/Plants14132032..
