Abstract: The essential oil extracted by hydrodistillation from the leaves of Piper guineense Schumach. & Thonn. (Côte d’Ivoire) showed a yield of 2.00 ± 0.01% (w/w). Combined analysis using gas chromatography–mass spectrometry (GC-MS) and ¹³C nuclear magnetic resonance (¹³C NMR) spectroscopy enabled the identification of 41 volatile compounds, classified into five groups: sesquiterpenes (92.46%), diterpenes (4.53%), monoterpenes (2.74%), linear alcohols (0.25%), and linear hydrocarbons (0.29%). The major constituents were hydrogenated azulene (20.54%), β-caryophyllene (19.54%), 1-(1-methylethyl)-4, 7-dimethyl-1,2,3,5,6, 8a-hexahydronaphthalene......
Keywords: Piper guineense; Essential oil; GC-MS; ¹³C NMR; Sesquiterpenes; β-Caryophyllene; Hydrogenated azulene
[1].
Adams, R. P. (2007). Identification Of Essential Oil Components By Gas Chromatography/Mass Spectrometry (4th Ed.). Allured Publishing Corporation.
[2].
Ademuyiwa, O. H., Ademosun, A. O., & Adefegha, S. A. (2023). The Potential Role Of Piper Guineense (Black Pepper) In Managing Brain Aging: A Review. Critical Reviews In Food Science And Nutrition, 63(19), 3035–3050.
[3].
Akinloye, O., Somade, O. T., & Oyewopo, A. O. (2020). Evaluation Of The Modulatory Effects Of Leaves And Seeds Of Piper Guineense On Egg Albumin-Induced Inflammation In Experimental Rat Models. Journal Of Ethnopharmacology, 258, 112927.
[4].
Bakkali, F., Averbeck, S., Averbeck, D., & Idaomar, M. (2008). Biological Effects Of Essential Oils – A Review. Food And Chemical Toxicology, 46(2), 446–475.
[5].
Bakun, P., Czarczynska-Goslinska, B., Goslinski, T., & Lijewski, S. (2021). In Vitro And In Vivo Biological Activities Of Azulene Derivatives With Potential Applications In Medicine. Medicinal Chemistry Research, 30, 834–846.