Volume-15 ~ Issue-8 ~ Aug. 2022

Abstract: Phytochemical analysis carried out on Moringa Oleifera leaf extract indicated the presence of alkaloids, saponins, flavonoids, reducing sugar, glycosides, and terpenoids. The antibacterial activity of the leaf extracts of M. oleifera on Staphylococcus Aureus and Escherichia Coli at different concentrations were analyzed, and the maximum zone of inhibition was observed at 15nm and 13nm respectively. Zone of inhibition was found to increase with increasing concentration of the Moringa Oleifera leaves extract..

Keywords. Phytochemicals, Antimicrobial, Medicinal plants, Antibacterial, Infectious diseases

[1]. Afolayan, A-J 2003. Ex-zac--s "-Yom the shoots of Arctictis actinoids inhibiting the growth of bacteria and fungi. Pharmacological Reviews., 41
[2]. Ahmad, S.M., Muhammed, S.K.S., and Abdulkarim, J.P. (2012). Physiochemical properties of Moringa oleifera seed oil extracted using solvent and enzymatic methods. Food Chemistry. 51(8) 21442155.
[3]. Aiyegoro F, Latif S, AshrafM, Gilani AH. Moringa oleifera: Evaluation of the antioxidant activity of plant extracts and their heat, pH, and storage stability. Food chemistry. 2008; 27: 17-25.
[4]. Aliero, M. and Afolayan A.J. (2006) Antioxidant and total phenolic content of moringa oleifera leaves in two stages of maturity. Plant food Human Nutrition 2009; 64:3-11.
[5]. Barry, S.I (1976). Some Physico-chemical properties of Moringa oleifera seed oil extracted using solvent and aqueous enzymatic methods. Food Chemistry. 93, 2, 253-263.

Abstract: Water is essential to life and access to safe and clean water is a basic need. Scarcity and pollution of water could have serious health implications. The study of water quality tells us about the present state of useable water for domestic as well as industrial use. This study aimed to determine water quality parameters in borehole water samples from Amukachi and Obiudo Akabo in Imo state, Nigeria. The water samples were collected and analyzed using different types of analytical techniques. The parameter analyzed and the results of their mean value on the physical and chemical parameters include: Color 22PCU, Temperature 26.6oC, Conductivity 9.95μS/cm, pH 5.77, TDS.......

Keywords. Groundwater; Water Quality; Industrial Use; WHO

[1]. Haseena M, Malik M. F., 2017. Water pollution and human health. Environ Risk Assess Remediat, 1(3):16-19.
[2]. Pawari M. J., Gawande S., 2015. Groundwater pollution and its consequence. International journal of engineering research and general science,
[3]. Alrumman S. A., El-kott A. F. and Kehsk M. A., 2016. Water pollution: Source and treatment. American journal of Environmental Engineering, 6(3):88-98.
[4]. Soladoye O. and Ajibade L. T., 2014. A Groundwater Quality Study of Lagos State. Nigeria International Journal of Applied Science and Technology, vol. 4, No. 4, pp. 271-281.
[5]. Akabo. Wikipedia, 22 October 2019.''https://en.wikipedia.org/wiki/Akabo''.

Abstract: The ability to separate adhesive bonded assemblies for structural applications without causing damage to the substrates is clearly very desirable. Thermally removable adhesive by incorporating thermally reversible furan–maleimide Diels–Alder adducts have also synthetized. They form at low temperature and dissociate at higher temperature in a low modulus epoxy adhesive formulation. The debonding mechanisms of dismantlable adhesives are mainly based on changes in the bulk properties of the adhesive, making competition between strong bonding and easy debonding by controlling the cohesiveness of the adhesive. Unwanted side reactions cause the formation of crosslinks that are not reversible in nature, thereby reducing the self-healing performance. Against......

Keywords. furan–maleimide Diels–Alder adducts synthesis, reactive blend, reversible/irreversible networks, thermal and thermomechanical analyses

[1] Luo K, Xie T, Rzayev J. Synthesis of thermally degradable epoxy adhesives. J Polym Sci Part Polym Chem 2013;51:4992–7. https://doi.org/10.1002/pola.26926.
[2] Kwart Harold, King Kenneth. The reverse Diels-Alder or retrodiene reaction. Chem Rev 1968;68:415–47. https://doi.org/10.1021/cr60254a002.
[3] Marref M, Mignard N, Jegat C, Taha M, Belbachir M, Meghabar R. Epoxy-amine based thermoresponsive networks designed by Diels–Alder reactions. Polym Int 2013;62:87–98. https://doi.org/10.1002/pi.4287.
[4] Tian Q, Chao Yuan Y, Zhi Rong M, Qiu Zhang M. A thermally remendable epoxy resin. J Mater Chem 2009;19:1289–96. https://doi.org/10.1039/B811938D.
[5] Gandini A, Coelho D, Silvestre AJD. Reversible click chemistry at the service of macromolecular materials. Part 1: Kinetics of the Diels–Alder reaction applied to furan–maleimide model compounds and linear polymerizations. Eur Polym J 2008;44:4029–36. https://doi.org/10.1016/j.eurpolymj.2008.09.026.

Abstract: A new PVC membrane sensor for enalpril based on enalpril-phosphotungstate ion pair. The influence of membrane composition (i.e. percent of PVC, plasticizer, ion-pair complex, and nature of plasticizer), inner filling solution, pH of test solution, and the presence of foreign cations on the electrode performance were be studied. The optimized membrane demonstrates Nernstian response (57.8 ± 1.0 mV per decade) forenalprilcations over a wide linear range from 1×10-6to 1×10-2 M at 25 oC. The potentiometric responseis independent of the pH in the range of 1.5-4.0. The proposed sensor has the advantages of easy preparation,fast response time. The selectivity coefficients indicate excellent selectivity for enalprilover many commoncations (e.g., Na+, K+, Mg2+, Ca2+, Ni2+,and severalorganic compounds(rhamnose, maltose, glycine and benzamide). The practical applicationsof this electrode wasdemonstrated by measuring the concentrations of enalprilin pure solutions andpharmaceutical preparations with excellent results

Keywords: Enalpril, Phosphotungstate, Ion Selective Electrode, Pharmaceutical Analysis, PVC-Membranes

[1]. Mohsen M. Zareh, Yasser M. Abd Alkarem et al., Novel Ionophore for the Potentiometric Determination ofPregabalin in its Pure Forms and in its PharmaceuticalFormulations, IOSR-JAC., 2021; (14): 34- 42.
[2]. Mohsen M. Zareh, Yasser M. Abd Alkarem et al., Plastic Sensor for Losartan Potassium Determination based on Ferroin and Ionic Liquid, Int. J. Electrochem. Sci., 2018; (13): 1260- 1274.
[3]. Mohsen M. Zareh, Yasser M Abd Alkarem et al., Electrochemical sensors for determination of Tranexamic acid in pure form and pharmaceutical preparations, 2016; (1): 5-12.
[4]. Mohsen M. Zareh, Yasser M. Abd Alkreem et al., Electrochemical Sensor for the Selective Determination of Prindopril Based on Phosphotungestic Acid Plastic Membrane, Bull. Korean Chem. Soc. 2013; (34): 3088-3092.
[5]. Nashwa M. Rizk, Yasser M. Abd EL-Karem et al., Thiopental and Phenytoin as Novel Ionophores for Potentiometric Determination of Lead (II) Ions, Sensors, 2009; (9): 1860-1875.

Abstract: Based on numerous variables, including density and atomic weight, heavy metals can be characterized in a variety of ways. In small amounts, several heavy metals like iron, cobalt, and zinc are necessary for human nutrition but are poisonous in larger amounts. However, only a few elements, like lead, cadmium, and mercury are toxic even in trace amounts.The concentration of essential metals such as Fe, Cu and Zn and toxic metals such as Pb, Cd, Cr, As and Ni were determined in a number of egg samples by using atomic absorption spectrophotometry (AAS).......

Keywords. Egg, Health risk, Heavy metals,Bagerhat&Bangladesh

[1] M. I. Omar, A. Islam, M S Hoq, M. F. Dewan, M. T Islam, IOSR Journal of Business and Management, 16 (2014) 52-58.
[2] A. S. Gallego, R. M. O. Anta, and F. T. Cosialls, InstitutodeEstudiosdelHuevo, Eggbook, 2001. [3] C. R. S. Paz, I. Ojeda, A. J. Gutierrez, D. G. Weller, A. Hardisson, C. Revert, Journal of Food Quality, 2017 (2017) 1-11.
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[5] G. R. Islam, F. E. Khan, M. M. Hoque, Y. N. Jolly, Environmental monitoring and assessment, 186 (2014) 7233-7244.
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Abstract: Diabetic nephropathy (DN) is a progressive kidney disease, and it is estimated to develop in one third of both main types of diabetes.New biomarkers are needed to improve the identification of individuals at increased risk of developing diabetes mellitus complications particularly DN. The currentstudy aimed to evaluate the diagnostic potential of two circulating microRNAs (miR-346 and miR-92a) as a non-invasive biomarker for DNintype 2 diabetesmellitus Egyptian patients.Atotalof90plasmasampleswerecollected (15 control,25normoalbuminuriapatients and50patients with DN that divided equally into microalbuminuria group and macroalbuminuria group, n= 25).The expressionlevelsof thetwo miRNAswerequantitatively detected usingreal-timePCR.Results revealed......

Keywords: Diabetes, Diabetic nephropathy,microRNA, miR-92a, miR-346

[1]. Hegazi, R., et al., Epidemiology of and Risk Factors for Type 2 Diabetes in Egypt. Annals of Global Health, 2015. 81(6): p. 814-820.
[2]. Rask-Madsen, C. and G.L. King, Vascular complications of diabetes: mechanisms of injury and protective factors. Cell metabolism, 2013. 17(1): p. 20-33.
[3]. Lim, A.K., Diabetic nephropathy - complications and treatment. International journal of nephrology and renovascular disease, 2014. 7: p. 361-381.
[4]. Afkarian, M., et al., Kidney disease and increased mortality risk in type 2 diabetes. J Am Soc Nephrol, 2013. 24(2): p. 302-8.
[5]. Umanath, K. and J.B. Lewis, Update on Diabetic Nephropathy: Core Curriculum 2018. Am J Kidney Dis, 2018. 71(6): p. 884-895.

Abstract: A novel ruthenium(III)-pyrimidine Schiff base was synthesized and characterized using different analytical and spectroscopictechniques.Molecular geometries of the ligand and rutheniumcomplex were investigated using the DFT-B3LYPlevel of theory. The quantum global reactivity descriptorswere also calculated.Various biological and molecular docking studies of the complex are reported to explore its potential application as therapeutic drug.Cytotoxicity of the complex was screened against cancer colorectal (HCT116), breast (MCF-7 and T47D), hepatocellular (HepG2) cell lines as well as human normal cell line (HSF).The complex effectively inhibited the tested cancer cells with variable......

Keywords:ruthenium Schiff base complex; DFT studies, antitumor activity, DNA damage, cell cycle arrest, apoptosis, molecular docking

[1]. Singal, A. G.,Lampertico, P.&Nahon, P. Epidemiology and surveillance for hepatocellular carcinoma: New trends. J. hepatol. 72, 250-261 (2020).
[2]. Petrick, J. L.et al.International trends in hepatocellular carcinoma incidence, 1978–2012. Int. J. cancer147, 317-330 (2020).
[3]. Jafri, W.& Kamran, M. Hepatocellular carcinoma in Asia: a challenging situation. EuroasianJ. HepatoGastroenterology9, 27-33 (2019).
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[5]. Lee, S. Y., Kim, C. Y.& Nam, T. G. Ruthenium complexes as anticancer agents: A brief history and perspectives. Drug Des. Devel. Ther. 14, 5375-5392 (2020)..

Abstract: This work was carried out in order to determine the agronomic value of composts from crop waste, on two market garden crops: tomato and lettuce. Thus, the effect of two types of compost (simple compost and phosphocompost) was monitored, the results of which are compared with those of NPK on the same crops. The experimental device used is a complete randomized block comprising three repetitions and four treatments by direct spreading of the three fertilizers. Soil samples taken at a depth of 0-20 cm were characterized. The results of characterized showed that it is a sandy soil with an acid pH (pH= 4.36) and poor in nutrients (nitrogen 0.03%, total phosphorus 5.28 mg/kg, assimilable phosphorus 4.55 mg/kg, potassium 2.3 meq/100g, magnesium 3.8 meq/100g, calcium 0.10 meq/100g.).....

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