Volume-14 ~ Issue-8 ~ Aug. 2021

Abstract: In human and animal bodies trace amount of transition metals such as Iron (Fe), Copper (Cu), Manganese (Mn) etc. are present. Fe is the most essential metal ion usage in hemoglobin for oxygen transport. Cu is one of the biologically important chemical species that functions as a co-factor in metalloenzymes and metalloproteins. Mn is also an important microelement for plants and adult human body. Electrochemical studies of such metal ions in presence of ligands have been carried out in order to understand the mode of interaction and electron transfer......

Keywords: Cyclic voltammetry, pH effect, Cu(II)-Valine complex, Chronamperometry (CA), UV-Vis and FTIR

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Abstract: The study presents a real time method based on non-invasive technique of NIR diffuse reflectance spectroscopy in qualitative and authentications of aflatoxins in sifted maize flour, amid claims of high levels of aflatoxin contamination in maize flour in Kenya. The differentiations of AFB1 with AFB2 and AFG1 with AFG2 were done on generated spectra using chemometric techniques. Aflatoxins were extracted from each flour sample and authenticated using HPLC on the basis of retention time (Rt). The remaining part of flour analyzed on NIR spectrometer equipped with InGaAs detector. Samples were partitioned randomly into calibration, validation and prediction. Calibration data was partitioned as per Kennard –Stone algorithm. An average of 32 scans were made on each sample and recorded. Multiplicative Scatter Correction, Savitzky –Golay, Standard Normale Variate Detrending and.......

Key words: Aflatoxins, NIR spectroscopy, Least Square- Support Vector Machine, Partial Least Square -Discriminant Analysis, Chemometrics, Qualitative Discrimination

[1]. Abookasis D and Workman J (2012): Direct Measurements of Blood Glucose Concentration in the Presence of Saccharide Interferences Using Slope and Bias Orthogonal Signal Correction and FT-NIR. Journal of Biomedical Optic 16 (2) 027001.
[2]. American standards For Testing Material (2013): Practice D2013/D2013M Provides instructions forreducing and dividing the gross or divided sample by on-line or off line.[3]. Berdahl M. and Kohler A. (2016): Analysis of Allergenic Pollen by FT-IR Micro spectroscopy. Journal of Analytical Chemistry 588(1) 803-11.
[4]. Bouabidi A., Rozet E., Fillet M., Ziemon E, Chauzet B and Hubert Ph (2010): Critical Analysis of Several Analytical Methods, Validation Strategy in the Framework of the Fill For Purpose Concept, Journal of Chromatography A1217:3180-3192.
[5]. Balabin R, Safieva R and Lomakina E (2010): Gasoline Classification Using NIR Spectroscopy Data: Comparison of Multi variate Techniques. Journal of Analytical Chemistry, 671:27-35..

Abstract: The activities of mosquito repellents produced from peels of orange and grape fruits were compared. The extracts of Citrus fruit peels were air-dried and powdered, soxhlet method was used for the extraction with diethyl ether as solvent. Three different repellents (Candle, Cream and liquid) were produced from each extract. Application of the products on human volunteers showed that the products repelled mosquitoes and other insects effectively. This study revealed that some phytochemical compounds found in the extracts were active ingredients which made the prepared repellents effective on all species of insects without having any harmful effect on the users. There were no significant difference in the results of physico-chemical parameters and repellent properties of the two studied citrus fruits..

Keywords: Production, Mosquito repellent, Orange, Grape, Peels

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Abstract: This paper studies the electrochemical reduction of p-aminoacetophenone in basic aqueous medium. This may provide a basis for attractive environmental friendly and sustainable syntheticprocedure. The reduction process was investigated cyclic voltammetrically to explore it as an alternative synthetic route for the preparation of alcohols. On electrolysis in basic medium (pH-9) controlled current in 1.0 M Sodium acetate, 1-(4-aminophenyl)ethanol was obtained as the major product, which was isolated, purified and characterized by combined application of chromatographic and spectroscopic techniques. Stainless steel (SS-316) electrodes were used as anode & cathode.

Keywords: p-aminoacetophenone, Stainless Steel (SS-316) Electrode, Cyclic Voltammetry, Controlled Current electrolysis.

[1]. B. A. Frontana-Uribe, R. D. Little, J. G. Ibanez, A. Palmaand R. Vasquez-Medrano, Organic electrosynthesis: a promising green methodology in organic chemistry;Green Chem., 2010, 12, 2099–2119.
[2]. E. J. Horn, B. R. Rosen and P. S. Baran, Synthetic Organic Electrochemistry: An Enabling and Innately Sustainable Method;ACS Cent. Sci.,2016, 2, 302–308.
[3]. Y. Yuan and A. Lei, Is electrosynthesis always green and advantageous compared to traditional methods?;Nat. Commun., 2020, 11, 802.
[4]. S. Mohle, M. Zirbes, E. Rodrigo, T. Gieshoff, A. Wiebe and S. R. Waldvogel, Angew. Chem., Int. Ed., 2018, 57, 6018–6041.
[5]. S. R. Waldvogel and B. Janza,Renaissance of Electrosynthetic Methods for the Construction of Complex Molecules;Angew. Chem., Int. Ed., 2014, 53, 7122–7123

Abstract:The use of AHC reagent has not been reported for the estimation of the antibiotics. therefore in the present chapter, I have described a simple method for the determination of following antibiotic drugs, such as Amoxicillin, Ampicillin, Cefixime, cloxacillin Sodium, Norfloxacin and Ornidazole in pure form and in their pharmaceutical preparations like Novamox-DT(Tab), Blumox-DT (Tab), Cincillin Introduction Rajeev Singh Baghel : 50 (Inj), roscillin (Inj), Cefexy (Tab) Hifen (tab), Klox (Inj), Neoclox (Tab), Uflox (Tab), Utibid (Tab), Giro (Tab) and Ornilox (Tab). Background: The word antibiotic comes from the Greek antibiosis, which is made up from anti meaning " against" bios means "life" (i.e. against......

Keywords: Micro Determination, Antibiotic Drugs.

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Abstract: Background: 1,3,4-Thiadiazoles display a wide spectrum of biological activities including anticancer, antimicrobial, antiviral, antiepileptic, antidiabetic, analgesic, and anti-inflammatory activities. In particular, recent studies have pointed out the significance of the 1,3,4-thiadiazole scaffold in the field of current cancer research. Materials and Methods: Novel 2,5-bis thiacarbohydrazono-1,3,4-thiadiazoles were designed, synthesized and their chemical structures were elucidated on the basis of elemental analyses and spectral data (FT-IR, 1HNMR, 13CNMR, mass spectra). In vitro antiproliferative activities were evaluated by viability assay against three types of human cancer cell lines, HepG-2, HCT-116 and MCF-7.....

Keywords: Thiadiazole; Bis carbohydrazides; Bis carbohydrazones; Antiproliferative; Viability; HepG-2; HCT-116 and MCF-7 cell lines

[1]. Glomb T, Szymankiewicz K, Swiatek P. Anti-Cancer Activity of Derivatives of 1,3,4-Oxadiazole. Molecules. 2018; 23: 3361.
[2]. Dawood KM, Gomha SM. Synthesis and Anti-cancer Activity of 1,3,4-Thiadiazole and 1,3-Thiazole Derivatives Having 1,3,4- Oxadiazole Moiety. J. Heterocyclic Chem. 2015; 52: 1400–1405.
[3]. Dawood KM, Farag AM, Abdel‐Aziz HA. Synthesis and antimicrobial evaluation of some 1,2,4-triazole, 1,3,4-oxa (thia) diazole,
and 1,2,4-triazolo [3,4-b]-1,3,4-thiadiazine derivatives. Heteroatom Chem. 2005; 16(7): 621–627.
[4]. Bakht MA, Yar MS, Abdel‐Hamid SG, Qasoumi SI, Samad A. Molecular properties prediction, synthesis and antimicrobial activity of some newer oxadiazole derivatives. Eur J. Med. Chem. 2010; 45(12): 5862–5869.
[5]. Fuloria NK, Singh V, Shaharyar M, Ali M. Synthesis and antimicrobial evaluation of some New Oxadiazoles Derived from Phenylpropionohydrazides. Molecules 2009; 14(5): 1898–1903.

Abstract: The study was carried out to assess some physical and chemical parameters of the water samples collected from different tube wells in the Rajshahi City Corporation Area, Bangladesh and justified the effectiveness of different water purifiers widely used in this area. Seven water samples from different locations were collected and analyzed for various physicochemical parameters. Besides, three water samples from three types of water purifiers were collected and analyzed to determine the effectiveness of those filters considering the drinking water quality. From this study, it was found that most of the parameters existed under the permissible limits of BD standards.

Keywords: Rajshahi City; Bangladesh; Water Quality; Water Purifier; Physicochemical Parameters

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Abstract: The objective of this work is the physico-chemical characterization of the wastewater of slaughterhouse of the urban commune of Mamou (Guinea) in order to propose an adequate treatment thus reducing the harmful consequences which undergoes the receiving environment (River Singuedala affluent of Bafing and this last affluent of the Senegal river) and to cure also the loss of this hydrous source in valorizable matters. The physico-chemical characterization of the raw wastewater revealed that this liquid discharge is highly loaded with organic matter in terms of COD (Avg. = 228.54 mg/L), BOD5 (Avg. = 218.39 mg/L), TSS (Avg. = 418.50 mg/L) and mineral matter expressed in terms of electrical conductivity (Avg. = 1427.25 μs/cm) with a pH of 7.06. The average.....

Keywords: wastewater, slaughterhouse, physicochemical, Mamou

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Abstract: Four complexes CoScplx, CoNcplx, NiScplx and NiNcplx were synthesized from 2-hydroxynaphthalene -1-carbaldehyde using 2-thiosylaniline and 2-aminoaniline as Co-Schiff bases. The physical and analytical data of the ligands and complexes such as Molecular weight, colour, melting point and percentage yield as well as molar conductivity and elemental composition were determined. The compounds were characterized using FT-IR, UV-VIS and MS Analyzers. FT-IR results revealed loss of –OH bond noticed in the ligands at complexation due to deprotonation and utilization of phenolic OH in bond formation. The UV-VIS spectral data recorded more peaks with Schiff bases and complexes with 2-aminoaniline as a result of more chromophoric groups. The MS result determined m/z of the molecular ions and their fragments confirming the structure of synthesized compounds. The complexes demonstrated more antifungal and antibacterial activities more than the ligands hence can be incorporated into antibiotics drugs in future..

Keywords: Synthesis, Characterization, Antimicrobial, 2-thiosylaniline, 2-aminoaniline

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