Volume-14 ~ Issue-3 ~ March 2021

Abstract:In the crystal structure of the title compound, [Fe(NCS)2(HL)2] (HL is 2-methoxy-6-((phenylimino)methyl)phenol), the six-coordinated Fe(II) cation is bonded with two O-phenolate, two O-ether and two N-thiocyanate anions. In the complex, the ligand molecule acts as zwitterion. The complex 1 is characterized by elemental analysis, conductance measurement, room temperature magnetic susceptibility measurement and IR spectroscopic study. The complex 1 crystallizes in the monoclinic sp. gr. P21/n, Z = 4. In the crystal, the FeII cation is in a N2O4 core and is situated in a distorted octahedral environment. Furthermore.....

Keyword: o-vanillin, aniline, thiocyanate, X-ray.

[1]. A. De, H. P. Ray, P. Jain, H. Kaur, N. Singh, Synthesis, characterization, molecular docking and DNA cleavage study of transition metal complexes of o-vanillin and glycine derived Schiff base ligand, J. Mol. Struct., 2020, 1199, 126901.
[2]. R. Gheorghe, G. A. Ionita, C. Maxim, A. Caneschi, L. Sorace, M. Andruh, Aggregation of heptanuclear [MII7] (M = Co, Ni, Zn) clusters by a Schiff-base ligand derived from o-vanillin: Synthesis, crystal structures and magnetic properties, Polyhedron, 2019, 171, 269.
[3]. V. A. Neacşu, C. Maxim, A. M. Mădălan, M. Hillebrand, C. González-Arellano, S. Soriano, E. Rentschler, M. Andruh, New complexes of Ni(II) and Co(III) with a Schiff-base ligand derived from o-vanillin. Crystal structure, magnetic and catalytic properties of a dissymmetric binuclear nickel(II) complex, Polyhedron, 2018, 150, 77.
[4]. Y.-X. Zhang, X.-Y. Cheng, Y.-T. Tang, Y.-H. Zhang, S.-C. Wang, H.-Y. Wei, Z.-L. Wu, Two dinuclear lanthanide(III) clusters (Gd2 and Dy2) constructed by bis-(o-vanillin) schiff base ligand exhibiting fascinating magnetic behaviors, Polyhedron, 2019, 166, 23.
[5]. Y.-J. Sun, W.-Z. Shen, P. Cheng, S.-P. Yan, D.-Z. Liao, Z.-H. Jiang, P.-W. Shen, The first example of half-sandwich cobalt(III) complex with hydrotris(pyrazolyl)borate ligand, Inorg. Chem. Commun., 2002, 5, 512.

Abstract: Method of static UV-VIS spectrophotometry were applied for the determination of protonation constants ofvalues of L-Tyrosine were determined in Dimethylformamide(DMF) and Ethylene Glycol(EG) - water mixtures (0–60% v/v) at 303.0 K at an ionic strength of 0.16 M. The log K values were found to be an increase with increase of the organic solvent content. Distribution of species, protonation equilibria and effect of influential parameters on the protonation constants have also been presented.

Keyword: L-Tyrosine, Dimethylformamide, Ethylene Glycol, Protonation constant, UV-VIS spectrophotometry.

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Abstract: The aim of the method is to develop analytical procedure for the determination of Bendamustine Hydrochloride in Pharmaceutical Formulations. The analytical procedure for determination of Assay in finished product of Bendamustine Hydrochloride in Bendamustine Hydrochloride for injection 25 mg and 100 mg per vial is an In-House procedure.The method shall be validated for the System precision, Method precision and Intermediate precision. The Chromatographic system consisted of a Shimadzu Class VP Binary pump LC-10ATvp, SIL-10ADvp Auto sampler, CTO-10Avp Column Temperature Oven, SPD-10Avp UV-Visible Detector. All the components of the system are controlled using SCL-10Avp System Controller. Data acquisition was done using LC Solutions software.

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Abstract: In recent years, many studies have been carried out on cement and its phases tounderstand the morphology, and to control the mineralogy of this material; due to the greatposition it has become globally occupied. This material is formed from a synthetic rock calledclinker; tricalcium silicate (Ca3SiO5 or C3S) its major constituent present a concentrationfrom 40% to 70%, and its solid solution with various impurities is called alite. Impure C3Sexhibits seven polymorphs from ambient temperature to 1500°C; three forms triclinic (T1, T2, T3), three monoclinic (M1, M2, M3) and one shape rhombohedral (R). At room temperature,impurities stabilize some of the high temperature forms of the pure compound. Those formsare related by transformation matrix determined in this article. The aim of the present paper isto investigate the structural modulations of alite.

Key words: Cement, clinker Portland, Polymorph, crystal structure, alite, space group, sub-group,matrix and coordinates system

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Abstract: Diazepam (DZ) drug-facilitated crime is frequently encountered in clinical and forensic toxicology cases due to misuse or abuse. This paper reports simple, sensitive, selective, reliable, rapid and expeditious GC–FID method for the quantitative analysis of diazepam (DZ) drug (1,4-benzodiazepines) in pure form, pharmaceutical preparations, urine, blood, biscuits and beverages, 1μg/ml clonazepam (CZ) as internal standard (I.S.) has been developed for different forensic toxicology laboratories. The chromatographic system of GC–FID was carried out without derivatization using a GC- 17AGas Chromatograph SHIMDZU in conjunction with a column (DP – 5, length: 30 meter and ID....

Key words: Diazepam; Clonazepam; GC–FID; Extraction; Stability; Urine, Blood, Biscuits and Beverages

[1]. C. S. Vlad, V. Dumitrascu, D. C. Vlad, A. Cimporescu, R. Popescu, L. Dehelean, I. Marincu, I. M. Citu, V. D. Poenaru, Fast and simple method for simultaneous detection and quantification of diazepam and desmethyldiazepam in plasma samples in psychiatric patients by GC-MS-FID. REV.CHIM. 68: 530–533 (2017)
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Abstract: Sardine fish oil has rich nutritional value as it composed of poly unsaturated fatty acid like omega-3 fatty acids. The present study has been focused on the characteristic deterioration of sardine fish oil conditional storage under irradiation by sun light. Oil on irradiation with sun light eight hour per day under goes rapid oxidation forming a peroxide value 49.6 meq/kg and 335.2meq/kg on first and ninth day in comparison with butylated hydroxyl toluene (BHT) as synthetic antioxidant and soy lecithin (SL) as natural antioxidant. Oil sample with BHT and SL recorded a minimum peroxide value 31.8 meq/kg and 94.8 meq/kg on the first and the ninth day. The combined anti-oxidative effect of BHT and SL to control the lipid oxidation is maximum as compared to individual anti-oxidative ability. The para asnisidine value (pAV) gives the secondary oxidation of fish lipids which is minimum for oil samples.....

Key words: Sun light, peroxide value, para-anisidine value (pAV), butylated hydroxyl toluene (BHT), soy lecithin (SL).

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Abstract: 4-nitro phenyl-1,3-bis(azo-3-methoxy aniline) was synthesized by diazotizing 4-nitro-1,3-phenylene diamine with sodium nitrite and concentrated hydrochloric acid at 00c and then coupling the diazonium salt with 2-methoxy aniline at 00c. The polyimide was synthesized by chemical imidization process. The azodye namely 4-nitro phenyl-1,3-bis(azo-3-methoxy aniline) and 6FDA in (1:1)molar ratio was stirred at 400C for 24h forming viscous polyamic acid solution then polyamicacid was treated with acetic anhydride and pyridine and stirred at1000C for 24h in the solvent medium of DMF giving the corresponding polyimide.

Key words: 4-nitro phenyl-1,3-bis (azo-3-methoxy aniline),polyamic acid, polyimide

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Abstract: Mining activities produce waste tailings that can be a significant source of pollution in the surrounding environment. This study was designed to assessed the ecological and human health risks of toxic metals (Cu, Zn, Cr, Ni,Cd, Pb, Hg, As) in mine tailings and soil from a lead mining area in Nasarawa-Eggon, Nasarawa State, Nigeria. The concentration of the selected metals were analysed in triplicate using AAS and the results for heavy metals in tailings samples ranged from 901.6 – 3475 mg/kg for Cu, 2026.8 – 3296 for Zn, 8.85 – 401.6 for Cd, 54.8 – 61.2 mg/kg for Cr 44.5 – 92.8 mg/kg for Ni, 42.3 – 4706.2 mg/kg for Pb, 0.023 – 0.041 mg/kg for Hg and 0.022 – 0.034 for As. Concentration of toxic metals reported for farm land soil samples also ranged from 20.8 – 57.8 mg/kg for Cu, 191.9 – 877.8 mg/kg for Zn, 20.6 – 23.8 mg/kg for Cd, 50.2 55.0 mg/kg for Cr, 2.67 – 95.8 mg/kg for Ni, 443.6 – 1087.5 mg/kg for Pb, 0.010 – 0.012 mg/kg for Hg and 0.012 – 0.015 mg/kg for As. The test results of tailings.....

Key words: Mine tailings, Heavy metals, Ecological, Human Health Risks

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