Abstract: Background: Gastro-esophageal reflux disease is a chronic disease that is widespread globally. This disease
                  negatively affects the patient's productivity and quality of life. Therefore, the patient's adherence to treatment
                  based on his health knowledge of the disease and its complications, as well as following a healthy lifestyle
                  positively affects their quality of life. Quite limited studies explored adherence of esophageal reflux patients and
                  their quality of life separately. Therefore, our study was aimed to determine the relationship between GERD
                  patients' knowledge, medication-adherence, and their quality of life.Research design: We used a quantitative
                  correlational design. Subjects: a convenience.......
                Keywords: Medication-Adherence, Compliance, Gastro-Esophageal Reflux [GERD], Knowledge, Lifestyle,
                  Quality of Life.
               
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