iosr-JDMS   Volume-21 ~ Issue-7 ~ July 2022

Abstract: BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a common, preventable and treatable disease that is characterized by persistent respiratory symptoms and airflow limitation which is not reversible due to airway and /or alveolar abnormalities usually caused by significant exposure to noxious particles or gases. Airflow limitation, also known as airflow obstruction in COPD determined for clinical purposes by Spirometry, which involves forced expiratory maneuvers after the subject has inhaled to total lung capacity. C-reactive protein (CRP) is a potential biomarker of systemic inflammation that is synthesized predominantly by the hepatocytes in response to tissue damage or inflammation.It is considered as prototypic downstream marker of inflammation. Serum CRP is more sensitive......

Keywords: Chronic obstructive pulmonary disease (COPD),High sensitive CRP

[1]. Vogelmeier CF, Criner GJ, Martinez FJ, Anzueto A, Barnes PJ, Bourbeau J, et al. Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary. Eur Respir J. 2017 Mar 1;49(3).
[2]. Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet (London, England). 2012 Dec;380(9859):2095–128.
[3]. Silvermn EK, Crapo JD, Make BJ. COPD. In: Jameson LJ, Kasper DL, Longo DL, Fauci AS, Hauser SL, Loscalzo J, editors. Harrisson's primciples of internal medicine. 20th.ed. USA: Mc Graw Hill; 2018. p. 1990–8.
[4]. Mathers CD, Loncar D. New projections of global mortality and burden of disease from 2002 to 2030 Protocol S1. Technical Appendix.
[5]. Calabró P, Willerson JT, Yeh ETH. Inflammatory Cytokines Stimulated C-Reactive Protein Production by Human Coronary Artery Smooth Muscle Cells. Circulation. 2003 Oct 21;108(16):1930–2..

Abstract: Takayasu arteritis (TA) is a rare, progressive, idiopathic vasculitis of aorta and its main branchesleading tostenosis, occlusion and aneurysm of the involved arteries. It is prevalent among young women in the reproductive age group. TA has an adverse effect on pregnancy outcome and there is an increased risk of complications. The overall prognosis is good when it is diagnosed early and patients receive regular antenatal follow up to prevent and manage the complications and to monitor the feto-maternal well being.Adopting a multidisciplinary approach for the management has shownimprove maternal and fetal outcome. We described here a case of pregnancy with TA involving the descending thoracic aorta and abdominal aorta with significant left subclavian artery stenosis and mild bilateral renal artery stenosis.

Keywords: Takayasu arteritis, Vasculitis, pregnancy, maternal outcome, fetal outcome, complications

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[6]. Hauenstein E, Frank H, Bauer JS, et al. Takayasu arteritis in pregnancy: review of literature and discussion. J Perinat Med. 2009;38(1):55-62.

Abstract: INTRODUCTION: The recurrence rate of optical internal urethrotomy (OIU) alone in the treatment of urethral stricture is approximately 50%.Pharmacological adjuncts to OIU,which can be injected at the site of OIU to significantly reduce the recurrence rate have been studied. One among such drugs is mitomycinC.If addition of this drug significantly lowers the recurrence rate of stricture formation,it will be very useful in the long term outlook of these patients. AIM: To study the efficacy of mitomycin C in reducing the recurrence rate of urethral stricture in patients undergoing Optical Internal Urethrotomy( OIU)......

KEYWORDS: Stricture urethra,Mitomycin C,Optical Internal Urethrotomy

[1]. Santucci RA, Eisenberg L. Urethrotomy has a much lower success rate than previously reported. J Urol. 2010; 183: 1859–62.
[2]. Mazdak H, Izadpanahi MH, Ghalamkari A, Kabiri M, Khorrami MH, Nouri-Mahdavi K, et al.Internal urethrotomy and intraurethral
submucosal injection of triamcinolone in short bulbar strictures. Int Urol Nephrol. 2009.
[3]. Shirazi M, Khezri A, Samani SM, Monabatti A, Kojoori J, Hassanpour A. Effect of Intraurethral captopril gel on the recurrence of
urethral stricture after direct vision internal urethrotomy:Phase II clinical trial. Int J Urol. 2008; 15: 562–4.
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Abstract: Arterial blood gas analysis is widely used and is a direct measurement of pH , PaO2 , PaCO2. The advent of arterial gas analysis has revolutionized the field of Respiratory medicine especially bronchial asthma. Aim: To compare and correlate the values of arterial blood gas analysis in patients with severe acute bronchial asthma Objectives: To measure PaO2,PaCO2 variations in pH, variations in bicarbonate levels in severe acute bronchial asthma. Settings and Design: It is a hospital based observational study conducted at Siddhartha medical college, Vijayawada, Andhra Pradesh during the period from May 2019 to July 2019. Methodology: 40 Patients aged between 25 to 75 years both male and female presented to hospital with severe acute attack of asthma are included in the study. Results: It is a hospital based observational study, patients tested for ABG analysis....

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[5]. Brenner BE,AbrahamE.,Simon RR, Position and Diaphoresis in Acute Asthma.. American Journal of Medicine ,June 1983-P-74(6):1005-9.

Abstract: Background: Ulnar collateral ligament (UCL) injuries of the metacarpophalangeal (MCP) joint of the thumb are common. Complete rupture can be a debilitating injury, resulting in decreased grip and pinch strength. Materials and Methods:Twenty consecutive patients with 20 complete tears of the ulnar collateral ligament of the thumb metacarpophalangeal (MP) joint were treated with primary repair using a miniature intraosseoussuture anchorand stabilized with JESS fixator. Results: Fourteen patients were evaluated by clinical examination or by questionnaire at an average of 8 months after repair.Loss of interphalangeal joint motion averaged 15° on the involved side versus the other side, while loss of MP joint motion averaged 10°. There was no signficant difference on stress testing measurements between repaired and nonrepaired.......

Key Words: suture anchor,intraosseous,ulnar collateral ligament,JESS fixator

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