iosr-JDMS   Volume-21 ~ Issue-3 ~ March 2022

Abstract: Background : Acute Organophosphorus poisoning is a medical emergency and is a preventable and treatable cause of mortality in Emergency department. Acute organophosphate insecticide poisoning can manifest 3 different phases of toxic effects, namely, acute cholinergic crisis, intermediate syndrome (IMS), and delayed neuropathy. Among them, IMS has been considered as a major contributing factor of organophosphate-related morbidity and mortality because of its frequent occurrence and probable consequence of respiratory failure. Hence, in the present study, we intended to evaluate the efficacy of FFP transfusion in prevention of IMS following OP poisoning..........

Keywords: Intermediate syndrome (IMS), Organophosphate poisoning (OP), Fresh frozen plasma, (FFP), ICU stays, Ventilator support, Mortality

[1]. World Health Organization. The Impact of Pesticides on Health: Preventing Intentional and Unintentional Deaths from Pesticide Poisoning. Available at: http://www.who.int/mental health/prevention/suicide/en/PesticidesHealth2.pdf [Last accessed: September 11, 2021]
[2]. Eddleston M. Patterns and problems of deliberate self-poisoning in the developing world. QJM. 2000;93(11):715-31.
[3]. Guven M, Sungur M, Eser B, Sari I, Altuntas F. The effects of fresh frozen plasma on cholinesterase levels and outcomes in patients with organophosphate poisoning. J Toxicol Clin Toxicol 2004a; 42:617–623.
[4]. Eddleston M, Buckley NA, Eyer P, Dawson AH. Management of acute organophosphorus pesticide poisoning. Lancet. 2008; 371(9612): 597–607.
[5]. Nurulain SM. Different approaches to acute organophosphorus poison treatment. J Pak Med Assoc. 2012, 62 (7):712-717.

Abstract: Nanodentistry aims towards the application of nanotechnology for the maintanence of oral health. Research in nanotechnology has gained significant momentum over the years and has it's implications in the field of endodontics. From modifications in the rotary file systems to pulp regeneration nanotechnology has come a long way. A better understanding of the nanomodified materials and the ongoing research in this emerging field would help to appreciate how these materials can be used in daily practice. It would be safe to say that nanotechnology would definitely be a game changer in improving the quality of endodontic treatment.

[1]. Chogle S, Kinaia BM, Goodis HE. Scope of nanotechnology in endodontics. Nanobiomaterials in Clinical Dentistry. 2019 Jan 1:517-39.
[2]. The American Heritage Science Dictionary Houghton Mifflin company (2005)
[3]. Sivaramakrishnan SM, Neelakantan P (2014) Nanotechnology in dentistry—what does the future hold in store? Dentistry 4:198
[4]. Shrivastava S, Bera T, Roy A, Singh G, Ramachandrarao P, Dash D (2007) Characterization of enhanced antibacterial effects of novel silver nanoparticles. Nanotechnology 18:1–9
[5]. Raura N, Garg A, Arora A, Roma M. Nanoparticle technology and its implications in endodontics: A review. Biomaterials Research. 2020 Dec;24(1):1-8.

Abstract: Background: Chronic Obstructive Pulmonary Disease is one of the most important cause of morbidity and mortality throughout the world. It is now the 4th leading cause of death in the world and it is expected to become the 3rd leading cause of death by 2022. In 2012, COPD was the cause of death in more than 3 million people and it accounted for 6% of all the deaths worldwide. The COPD burden is expected to rise in coming years because of continuous exposure to risk factors and ageing of the population. The aim of this study is to study the clinical profile of patients and to assess right ventricular dysfunction by utilizing right ventricular parameters obtained by clinical methods, electrocardiography & echocardiography and to correlate with the severity of COPD according to GOLD guidelines.......

Key Word: COPD, Corpulmonale, ECG, 2D ECHO

[1]. Lozano R, Naghavi M, Foreman K, et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010.Lancet 2012; 380(989):209-128.
[2]. Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 20340. PloS Med 2006 ; 3(11): e 442.
[3]. Eisner MD, Anthnisen N, CoultasD,et al. An official American Thoracic Society public policy statement: Novel risk factors and the global burden of chronic obstructive pulmonary disease. Am J RespirCrit Care Med 2010; 182(5):693-718.
[4]. Paulin LM, Diette GB, Blanc pd, et al. Occupational exposures are associated with worse morbidity in patients with chronic obstructive pulmonary disease. Am J RespirCrit Care Med 2015;191(5):557-65.
[5]. Stoller JK, Aboussouan LS, Alpha 1 antitrypsin deficiency. Lancet 2005, 365(9478); 2225-36

Abstract: Introduction: Appendiceal mucocele is a clinically and pathologically rare condition. Mucinous secretions obstruct the lumen of the appendix leading to dilation. Case presentation: A 54-year-old female presented with right lower quadrant pain for three days. The pain was described as cramping, with nausea and vomiting following it. The imaging studies revealed a well-circumscribed mass with a smooth thin wall, without calcifications arising from the inferomedial aspect of the caecum, highly suggestive of an appendiceal......

Keywords: Appendicitis; Mucocele; Mucinous cystadenoma; Appendix; Appendectomy

[1]. Marudanayagam R, Williams GT, Rees BI. Review of the pathological results of 2660 appendicectomy specimens. J Gastroenterol. 2006;41(8):745-749. doi:10.1007/s00535-006-1855-5.
[2]. Naraynsingh V, Hariharan S, Sammy I. Cecal volvulus and mucocele of the appendix. Acta Gastroenterol Latinoam. 2010;40(4):354-356.
[3]. Jayakrishnan TT, Zacharias AJ, Sharma A, Pappas SG, Gamblin TC, Turaga KK. Role of laparoscopy in patients with peritoneal metastases considered for cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC). World J Surg Oncol. 2014;12:270. doi:10.1186/1477-7819-12-270.
[4]. Morano WF, Gleeson EM, Sullivan SH, et al. Clinicopathological Features and Management of Appendiceal Mucoceles: A Systematic Review. Am Surg. 2018;84(2):273-281.
[5]. Demetrashvili Z, Chkhaidze M, Khutsishvili K, et al. Mucocele of the appendix: case report and review of literature. Int Surg. 2012;97(3):266-269. doi:10.9738/CC139.1.