iosr-JDMS   Volume-16 ~ Issue-5 ~ May-2017

Abstract: Berger first described the glomerulonephritis now termed IgA nephropathy. IgA nephropathy (IgAN) is the most common form of glomerulonephritis in the world, and currently is known to be an importantcause of end stage renal disease (ESRD). It is classically characterized by episodic hematuria associated with the deposition of IgA in the mesangium. There is a male preponderance , a peak incidence in the second and third decades of life, and rare familial clustering. The most typicalpresentation is macroscopic hematuria shortly after amucosal infection such as upper respiratory tract infectionand bronchitis. Patients rarely present with nephritic syndrome. It is now well-known that prognosis is highlyvariable

[1]. Li LS, Liu ZH. Epidemiologic data of renal diseases from a single unit in China: Analysis based on 13,519 renal biopsies. Kidney Int. 2004; 66: 920–923.
[2]. Berthoux FC, Mohey H, Afiani A. Natural history of primary IgA nephropathy. Semin Nephrol. 2008; 28: 4-9.
[3]. Fogo AB, Kashgarian M. Diagnostic atlas of renal pathology. 1st ed. Spain: Elsevier-Saunders; 2005. p. 107-120.
[4]. Floege J, Eitner F. Immune modulating therapy for IgA nephropathy:Rationale and Evidence. Semin Nephrol. 2008; 28: 38-47
[5]. Barratt J, Feehally J. IgA nephropathy. J Am Soc Nephrol. 2005; 16: 2088–2097.
[6]. Tumlin JA, Madaio MP, Hennigar R. Idiopathic IgA nephropathy: pathogenesis, histopathology, and therapeutic options. ClinJ Am Soc Nephrol. 2004; 2: 1054-1061.

Abstract: Background: Nephrotic Syndrome is a common childhood illness. Major problem with this disease is frequent relapse. So, it is important to identify the children at risk for relapses to treat and further follow up. Aim &Objective: Aim of present study was to determine Spot PCR is a strong indicator of relapse in Nephrotic Syndrome. The primary objective of study was to determine the correlation between acute phase Spot PCR and subsequent relapses in Nephrotic Syndrome. Material and Method of study: Sixty two Nephrotic Syndrome children were included in this prospective cohort study at ICH&RC Madurai Medical College & Hospital. Spot PCR was estimated at the acute phase of disease before starting steroid therapy. They were followed up for six months from the time of remission to determine the further relapse.............

Keywords: Nephrotic syndrome, Spot PCR, steroid therapy.

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Abstract: Spinal Cord Injury is a global epidemic. It results in partial or complete disability. The life expectancy of these patients is also increased. The rehabilitation team is addressing physical needs. To assess the sexual need and related stress among patients with disability related to SCI and their spouses a descriptive study was conducted in in the Physical Medical and Rehabilitation OPD, Rehabilitation institute of the Christian Medical College, Vellore and the nearby villages in Vellore . The sample size was 30 patients and 30 spouses, chosen by purposive sampling technique...........

[1]. Rich Hansen Spinal Cord Injury Registry (2006) – Spinal Cord Injury Facts and Statistics. www.Spinalcord.uab.edu.
Retrieved on 13.04.2010.
[2]. Indian Spinal Injuries Center. – New Delhi Peer Counseling. http:/isiconline,org/rehabilitation.peer.html . Retrieved on 17
.04.2010.
[3]. Titch, Radnitz and Bauman, Depression and Spinal Cord Injury: A Monozygotic Twin study, Journal of Spinal Cord Medicine,
Vol. 22, No. 4, Winter, 1999, 284-287. Retrieved on 25.04.2010.
[4]. Sharma.et.al.(2006)Assessment of sexual functions after spinal cord injury in Indian Patients – International Journal of
Rehabilitation Research –Volume-29 –Issue -! PP 17-25 Retrieved on 25/04/2010.
[5]. Lee.X.Blonder ,Shelby, Creed , Pettigrew, Thomas ( 2007 ) The effects of stroke disability on spousal caregivers. Journal Neuro
Rehabilitation 22 P.85-92

Abstract: Objective: Alcohol has direct toxic effect on bone marrow and also indirect effect on precursors of all blood cells - red blood cells, platelets and white blood cells. Long term excessive alcohol consumption can interfere with various physiological, biochemical and metabolic processes of the blood cells. The medical consequences of haematological abnormalities can be severe and debilitating. The aim of this study is to evaluate frequency and nature of haematological parameters in inpatients with alcohol dependence syndrome and to study the relationship between haematological parameters and clinical variables.............

Keywords: Alcohol Dependence Syndrome, Anaemia, Thrombocytopenia.

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