Abstract: Atopic dermatitis, a chronic inflammatory skin disease, is characterized by severe itching of the skin and long-lasting eczematous lesions, which are thought to be a response to local allergens including house dust mites (HDM). Through previous studies, we confirmed that ALOVEtamer, a modified form of ALtamer (DNA fragment) composed of Aloe aptamers from Aloe vera and Aloe ferox varieties, specifically binds to derivative of viniferin extracts (VED) and increases stability and antioxidant effects. In addition, ALtamer has been shown to have an anti-inflammatory effect on skin inflammation through HDM mouse experiments, and it is being developed as an oral Nutrient Delivery......
Keywords: atopic dermatitis; house dust mites; Aloe ferox; Aptamer; glial cell line-derived neurotrophic factor, oral Nutrient Delivery System (NDS), skin Transdermal Delivery System (TDS)
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