Version-1 (May-June 2018)
- Citation
- Abstract
- Reference
- Full PDF
- Index Page
- Cover Paper
| Paper Type | : | Research Paper |
| Title | : | HsCRP And Serum Zinc Levels In Type 2 Diabetes Mellitus And Their Correlation With GLYCEMIC Status |
| Country | : | India |
| Authors | : | Dr .Mamatha B.V || Dr. Leela P || Dr. Chandrakanth K.H || Dr. Kashinath R.T |
 |
: | 10.9790/264X-0403010104  |
Abstract: Background: Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder in which prevalence has been increasing steadily all over the world. Type 2 DM represents a significant global health problem. Metabolically triggered inflammation has been proposed as a key step in the pathogenesis of this disease and accelerate atherosclerosis and premature death in subjects. C-reactive protein is an acute phase reactant protein., which is found elevated and serum zinc levels are lower in T2DM. Objectives: To estimate hsCRP (high sensitivity C reactive protein) and serum zinc levels in cases and controls and to compare and analyze the levels of these parameters between two groups............
Key words: T2DM; hsCRP; serum Zinc ; inflammation ; Oxidative stress.
[1]. Abdulfatai B. Olokoba, Olusegun A. Obateru, Lateefat B. Olokoba . Type 2 Diabetes Mellitus: A Review of Current Trends. Oman Medical Journal (2012) Vol. 27, No. 4: 269-273
[2]. Amanullah S, Jarari A , Govindan M , Basha MI and khatheeja S. Association of hs-CRP with Diabetic and Non-diabetic Individuals. JJBS 2010Jan;3(1);7-12.
[3]. Badawi A , Klip A, Haddad P, Cole DE, Bailo BG, Sohemy AE, Karmali M. Type 2 diabetes mellitus and inflammation: Prospects for biomarkers of risk and nutritional intervention, Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2010;3:173–86.
[4]. Pradhan AD, Manson JE, Rifai N, Buring JE, Ridker PM. C-Reactive Protein, Interleukin 6, and Risk of Developing Type 2 Diabetes Mellitus. JAMA 2001July;286(3).
[5]. Haque AF, Ekram AS, Islam QT, Jahan S, Haque Z. Evaluation of serum high sensitivity c -reactive protein (hs-CRP) in type-2 diabetic patient. J Medicine 2010; 11:20-3.
- Citation
- Abstract
- Reference
- Full PDF
| Paper Type | : | Research Paper |
| Title | : | Antimicrobial Activity Of Murraya Koenigii And Zingiber Officinale Plants On Drug Resistant Pathogens Isolated From Clinical Specimens And Preliminary Phytochemical Analysis Of The Crude Extract Preparations |
| Country | : | India |
| Authors | : | Nagesh Malik || Samreen Ahmed |
|
: | 10.9790/264X-0403010510 |
Abstract: The aim of the present study was to investigate the antimicrobial activity and phytochemical screening of Murraya koenigii and Zingiber officinale plant extracts. Ethanol and Methanol were used as the solvents for extraction. The antimicrobial activities of these plant extracts were tested against the drug resistant Gram-positive and Gram-negative bacterial strains. The bacteria used in the study were Staphylococcus aureus, Staphylococcus epidermidis, Acinetobacter baumannii, Salmonella spp., Proteus mirabilis, Escherichia coli, Pseudomonas aeruginosa, Enterococcus faecium and Neisseria spp. The ethanol and methanol extracts of leaves of Murraya koenigii and rhizome extracts of Zingiber officinale showed promising results against the drug resistant pathogens with zone diameter of inhibition more than 15mm. The ethanol extracts gave larger zones of inhibition than methanol extracts...........
Key words: Antibacterial activity, Drug resistant pathogens, ethanol, methanol, Phytochemical screening
[1]. Alo, M. N, Anyim, C., Igwe, J. C., Elom, M. and Uchenna, D. S. 2012. Antibacterial activity of water, ethanol and methanol extracts of Ocimum gratissimum, Vernonia amygdalina and Aframomum melegueta. 3:844-848.
[2]. Bipul Biswas, Kimberly Rogers, Fredrick McLaughlin, Dwayne Daniels and Anand Yadav. 2013. Antimicrobial Activities of Leaf Extracts of Guava (Psidium guajava L.) on Two Gram-Negative and Gram-Positive Bacteria. 2013:7.
[3]. Chang-Geun Kang, Dae-Sik Hah, Chung-Hui Kim, Young-Hwan Kim, Euikyung Kim and Jong-Shu Kim. 2011. Evaluation of Antimicrobial Activity of the Methanol Extracts from 8 Traditional Medicinal Plants. 27:31-36.
[4]. Chitra Wendakoon, Peter Calderon and Daniel Gagnon. 2011. Evaluation of Selected Medicinal Plants Extracted in Different Ethanol Concentrations for Antibacterial Activity against Human Pathogens. 1:60-68.
[5]. David G.White, Shaqua Zhao, Robert Sudler, M.S., Sherry Ayers, Sharon Friedman, Sheng Chen, Patrick F. Mcdermott, Shawn Mcdermott, B.S., David G. Wagner and Jianghong Meng. 2001. The Isolation of Antibiotics-Resistant Salmonella from Retail Ground Meats. 345.
- Citation
- Abstract
- Reference
- Full PDF
| Paper Type | : | Research Paper |
| Title | : | Apolipoproteins: Risk Assessment Tools For Coronary Heart Disease |
| Country | : | India |
| Authors | : | Dr.Leela .P || Dr.Mamatha .B.V || Dr.Chandrakanth .K.H || Dr.Kashinath .R.T |
|
: | 10.9790/264X-0403011115 |
Abstract: Myocardial Infarction (MI) is one of the major causes of morbidity and mortality in the world. Dyslipidemia is one of the important risk factor. It initiates atherosclerotic plaque formation, finally resulting in degeneration of endothelial cell function which enhances the coagulability of blood by activation of various factors for which apolipoproteins have been implicated. Apolipoprotein A-1 (apo A1) and apolipoprotein B (apo B) are the protein constituents of high density lipoprotein cholesterol (HDL-C) and low density lipoprotein cholesterol (LDL-C), respectively. Apo A-1 and HDL-C are antiatherogenic whereas Apo B and LDL-C are atherogenic. Objectives: To evaluate and to compare the serum concentrations of apo A1, apo B and lipid profile between Coronary Heart Disease (CHD) patients and healthy subjects and to establish interrelationship if any, between apolipoproteins and lipid profile in CHD patients............
Key words: Coronary heart disease, apolipoprotein, lipid profile, dyslipidemia.
[1]. Dutta S, Iqbal Z, Prasad KR. Comparison between serum hsCRP and LDL cholesterol for search of a better predictor for Ischemic heart disease. Ind J ClinBiochem 2011 Apr- June;26(2):210-13.
[2]. Rifai N, Warnick GR. Lipids, lipoproteins, apolipoproteins and other cardiovascular risk factors. In: Burtis CA, Ashwood ER and Bruns DA, editors. Tietz Text Book Of Clinical Chemistry and Molecular Diagnostics, 4th ed. New Delhi: Elsevier Co;2006:903-64.
[3]. Sharma R, Singh VS. Serum apolipoproteins in the patients of myocardial infarction in different age groups. Ind J ClinBiochem 2001;16(1):122-26.
[4]. Rifai N, Bachorik PS and Albers JJ. Lipids, lipoproteins, apolipoproteins and other cardiovascular risk factors. In: Burtis CA, Ashwood ER and Bruns DA, editors. Tietz Fundamentals of Clinical Chemistry, 5th ed. New Delhi: Elsevier Co;2006:903-64.
[5]. Irshad M, Dubey R. Apolipoproteins and their role in different clinical conditions: An overview. Indian Journal of Biochemistry & Biophysics 2005 April;42:73-80.
- Citation
- Abstract
- Reference
- Full PDF
| Paper Type | : | Research Paper |
| Title | : | Diagnostic Value Of Resistin And Hepcidin In Neonatal Sepsis |
| Country | : | Egypt |
| Authors | : | Khalifa AS || Mabrouk MM || Al-Zahrani Akh || Taha AA || Eed EM |
|
: | 10.9790/264X-0403011621 |
Abstract: Diagnosis of sepsis-attributed morbidity and mortality in the neonates still constitute a great challenge. Several attempts have been described to evaluate new diagnostic markers. Resistin and hepcidin are relatively new biomarkers that have been investigated and suggested as possible markers of infection in adult. The aim of this study was to evaluate hepcidin and resistin as new biomarkers of neonatal sepsis (NS) in comparison to the established diagnostic methods as C-reactive protein (CRP), blood culture and detection of bacterial 16S rDNA by PCR. The study included 150 neonates with suspected NS who were subjected to sepsis screen scoring. Complete blood count, CRP and automated blood culture were performed. Broad range bacterial 16S rDNA was detected by PCR without prior............
[1]. Shah BA and Padbury JF (2014). Neonatal sepsis; an old problem with new insights. Virulence. 5:170–78.
[2]. Reier-Nilsen T, Farstad T, Nakstad B (2009). Comparison of broad range 16S rDNA PCR and conventional blood culture for diagnosis of sepsis in the newborn: a case control study. BMC Pediatr. 9:5–12.
[3]. Van Rossum AM, Wulkan RW, Oudesluys-Murphy AM (2004). Procalcitonin as an early marker of infection in neonates and children. Lancet Infect Dis. 4(10):620-30.
[4]. Fattah MA, Omer AF, Asaif S (2017). Utility of cytokine, adhesion molecules and acute phase proteins in early diagnosis of neonatal sepsis. J Nat SciBiol Med. 8(1):32-39.
[5]. Tilg H, Moschen AR (2006). Adipocytokines: Mediators linking adipose tissue, inflammation and immunity. Nat Rev Immunol. 6:772-83.
- Citation
- Abstract
- Reference
- Full PDF
| Paper Type | : | Research Paper |
| Title | : | Adulteration And Its Mitigation By Phytochemical And Anatomical Screening Of Family Liliaceae |
| Country | : | Turkey |
| Authors | : | Farah Parveen || M.P. Singh |
|
: | 10.9790/264X-04030122284 |
Abstract: Endangered medicinal plants have been used as traditional and alternative medicines from last several decades. Deforestation and extinction of many medicinal plant species may leads to scarcity of these plants and was resulted in adulteration. In India, of the 8000 species of medicinal plants harvested from the wild, approximately 960 are in the active trade. Adulteration in market sample is one of the greatest drawback in promotion of herbal medicinal plant products. Future of herbal medicine totally depends upon the correct identification, standardization and quality assurance. Comparative anatomical study and phytochemical screening may be used for its correct authentication............
Key words: Adulteration, Herbal plant, Phytochemicals, Saponins.
[1]. Avijit Mazumber et al. 2002. Phytochemical observation on leaf of Lagerstroemia parviflora (Roxb); Ancient Science of life vol. XXII (2). [2]. Bordia, PC, Joshi, A, Simlot, MM 1995. Safed Musli Chadha, KLGupta, R.eds. Advances in Horticulture: Medicinal and Aromatic PlantsMalhotra Publishing HouseNew Delhi440449
[3]. Canter H P, Thomas H, Ernst E. 2005. Bringing Medicinal Plants Into Cultivation: Opportunities And Challenges For Biotechnology. Trends In Biotechnology Vol 23, No. 4.
[4]. Kirtikar KR, Basu BD. 1975. Indian Medicinal plants. M/s Periodical experts. New Delhi. Vol. 3. 2ml edition (Reprint 1975). 1933: 1734-1737. 1702.
[5]. Li X-C, Wong D-Z & Yang C-R 1990. Steroidal saponins from Chlorophytum malayense. Phytochemistry 29: 3893–3898
- Citation
- Abstract
- Reference
- Full PDF
| Paper Type | : | Research Paper |
| Title | : | Evaluation Of Rapd Analysis To Differentiate The Genotypes Of 11 Musa Cultivars |
| Country | : | India |
| Authors | : | Saifuldeen Ahmed Hasan || Shaik Mahammad Khasim |
|
: | 10.9790/264X-0403012936 |
Abstract: Evaluation of RAPD technique in differentiating the genotypes of 11 Musa cultivars. RAPD and UPGMA analysis was carried out to differentiate the genotypes of 11 Musa cultivars. Among the 08 primers, OPC-06 demonstrated highest number of amplicons while OPA-11displayed the least amplicons. The dendrogram OPR-08 displayed three clusters and one outlier that differentiated 11 Musa cultivars into 4 genotypes (AAA, AAB, ABB and AB). Among the primers employed in the study, OPR-08 was found to be efficient in differentiating the genotypes of 11 Musa cultivars. The present study recommends further investigation for the validation of OPR-08 primer in the differentiation of the Musa cultivar genotypes.
Key words: Musa cultivars, Banana, RAPD, Phylogenetic analysis.
[1]. G. Manzo-Sánchez, M.T. Buenrostro-Nava, S. Guzmán-González, M. Orozco-Santos, Muhammad Youssef and Rosa Maria Escobedo-Gracia Medrano. Genetic Diversity in Bananas and Plantains (Musa spp.), Molecular Approaches to Genetic Diversity, Prof. MahmutCaliskan (Ed.), InTech2015.
[2]. Ray T, Dutta I, Saha P, Das S, Roy SC. Genetic stability of three economically important micropropagated banana (Musa spp.) cultivars of lower Indo-Gangetic plains, as assessed by RAPD and ISSR markers. Plant Cell, Tissue Organ Cult 2006; 85(1):11-21.
[3]. Dickinson A. Recommended intakes of vitamins and essential minerals. CRN (Council for responsible Nutrition). The benefits of Nutritional Supplements 2000.
[4]. Simmonds NW. The Evolution of the Bananas. Longmans; 1962.
[5]. Simmonds NW, Shepherd K. The taxonomy and origins of the cultivated bananas. Bot. J. Linn. Soc1955; 55(359):302-12.
- Citation
- Abstract
- Reference
- Full PDF
| Paper Type | : | Research Paper |
| Title | : | A Review on CRISPR/CAS9 And Its Application in Research, Industry and Health Biotechnology |
| Country | : | Nigeria |
| Authors | : | Maryam Ammani Lawal || Gregory Elayeche Oko |
|
: | 10.9790/264X-0403013741 |
Abstract: Genome editing is a process that target and break down DNA at specific areas in the genome. In this review we discussed about methods use in gene editing such as Zinc fingers (ZFs), transcription activator-like effectors (TALEs) and CRISPR /Cas9 but the main focused was CRISPR /Cas9 in which we discussed about its application in research, industry and health biotechnology. In conclusion CRISPR /Cas9 can be used in treatment of cancer, HIV, sickle cell, antimicrobial resistance and other diseases.
Key words: Genome editing, CRISPR/ Cas9, germ line studies, antimicrobial resistance
[1]. Ain, Q. U., Chung, J. Y., & Kim, Y. H. (2015). Current and future delivery systems for engineered nucleases: ZFN, TALEN and RGEN. Journal of Controlled Release , 205, 120-127.
[2]. Barrangou, R., & Horvath, P. (2012). CRISPR: new horizons in phage resistance and strain identification. Annual review of food science and technology, , 3, 143-162.
[3]. Barrangou, R., & May, A. P. (2015). Unraveling the potential of CRISPR-Cas9 for gene therapy. Expert Opinion On Biological Therapy , 15 (3), 311-314.
[4]. Barrangou, R., & van Pijkeren, J. P. (2016). Exploiting CRISPR–Cas immune systems for genome editing in bacteria. . Current opinion in biotechnology , 37, 61-68.
[5]. Barrangou, R., Coûté-Monvoisin, A. C., Stahl, B., Chavichvily, I., Damange, F., Romero, D. A., et al. (2013). Genomic impact of CRISPR immunization against bacteriophages. Biochemical Society Transactions , 41 (6), 1383-1391;.
- Citation
- Abstract
- Reference
- Full PDF
| Paper Type | : | Research Paper |
| Title | : | Comparison Of Anti-Dandruff Activity Of Synthetic Shampoos And Crude Plant Extracts On Dandruff Causing Isolates |
| Country | : | Nigeria |
| Authors | : | Obasi Chinelo J. || Obasi Innocent S. || Okafor Ugochukwu C. || Uzoka || Ijeoma S. |
|
: | 10.9790/264X-0403014246 |
Abstract: Dandruff is very rampant and the market loaded with antidandruff shampoos and other skin care products, There is need to assume resourceful research into this area, To check the antidandruff activity of such antidandruff products, experiments was carried out on Malassezia furfur the causal organism for dandruff which was isolated using SDA with olive oil. The anti-dandruff activities of the synthetic shampoos and plant extracts were compared. Among the plant extracts tested, Lemon showed the highest zone of inhibition followed by lime, Neem plant and aloe vera while among the synthetic antidandruff shampoo venoz showed the highest zone of inhibition followed by Adal A hair shampoo...........
Key words: Dandruff, Synthetic products, Shampoo, Plant extract and Malassezia furfur.
[1]. DeAngelis Y. M, Gemmer C. M, Kaczvinsky J. R, Kenneally D. C, Schwartz J. R, Dawson T. L (2005): Three etiologic facets of dandruff and seborrheic dermatitis: Malassezia fungi, sebaceous lipids, and individual sensitivity". The Journal Investigative Dermatology Symposium Proceedings, 10 (3): 295–297.
[2]. Arora, P., Nanda, A. and Karan, M. (2011): Plants used in management of Dandruff. The Indian Pharmacist, 28-31.
[3]. Singla chhavi, Drabu sushma, and Ali Mohammad.( 2011) :Potential of herbals as antidandruff agents". International Research journal of Pharmacy, 2(3):16-18.
[4]. Vijayakumar R., Muthukumar, C., Kumar,T., and Saravanamuthu.R. (2006) "Characterization of Malassezia furfur and its control by using plant extracts". Indian Journal of Dermatology, 51 (2):145-148.
[5]. Lee, Jeong-Hyun and Jae-Sug Lee (2010) "Chemical composition and Antifungal Activity of Plant Essential Oils Against Malassezia furfur" Korean Journal of Microbiology and Biotechnology, 38: (3)315-321..
- Citation
- Abstract
- Reference
- Full PDF
| Paper Type | : | Research Paper |
| Title | : | Enzymatic Analysis Of Activity Of Metal Ions On Soybean(Glycine Max) lipase |
| Country | : | India |
| Authors | : | Dr. Jyoti D. Vora || Mr. Deep J. Gutka || Ms. Shivani Hasabnis |
|
: | 10.9790/264X-0403014751 |
Abstract: Considering the fundamental and practical aspect regarding the lipase activity,we studied the action of various pH and metal ions (Ca+2, Mg+2, Na+) on the activity of catalyzing property of crude lipase extracted from germinating soya bean. The pH 8.0 was found to yield the maximumlipase activity when compared with other fractionsof pH.Theaddition of divalent cations improved the overall activity, when compared to the control and other metal ions.It was concluded that the pH 8.0and divalent cation as activator improved the lipase activity..
Key words: activators, enzyme kinetics, lipase, metal ions, soya-bean lipase
[1]. Chougule, V.P. Zambare and M.V. Padul,Biochemical Studies ofLipase from Germinating Oil Seeds (Glycine max). American Journalof Biochemistry and Biotechnology 7 (3): 141-145, 2011.
[2]. Plummer, D. An introduction to practical biochemistry.
[3]. Harvey, R and Champe, P.Lippincottbiochemistry, London.2005
[4]. Boyer, R. Concepts in biochemistry. John Wiley and sons, New York.2002
[5]. https://en.wikipedia.org/wiki/Soybean
- Citation
- Abstract
- Reference
- Full PDF
| Paper Type | : | Research Paper |
| Title | : | Biochemical Role Of Lipoxygenase In Development Of Off Flavors, Bleaching Of Pigments And Dough Formation |
| Country | : | India |
| Authors | : | Dr. Jyoti D. Vora || Ms. Shivani Hasabnis || Mr. Deep J. Gutka |
|
: | 10.9790/264X-0403015257 |
Abstract: Soybean is one of the important ingredients in the food industry. It is one of the important protein source for all vegetarians, containing most of the essential amino acid required by the body. But its use can also have a negative consequence on the food product by means of unfavorable sensory characteristics. This is brought about by the activity of Lipoxygenase, a non-heme iron containing enzyme. It is involved in peroxidation of polyunsaturated (cis, cis-1, 4-pentadiene moiety) fatty acids in the presence of molecular oxygen. The biochemistry of the enzyme lipoxygenase has been reviewed. The mechanism of the action of Lipoxygenase has been studies but the presence of certain loopholes still exists. The aim of this review is to bridge the gap as effectively as possible. The positive and negative implications of the enzyme activity have also been discussed.........
[1]. Addition of Soybean Lipoxygenase to All-PurposeFlour and its Effects on Dough Gluten Strengthand Bread Quality, Erin M. Danielson.
[2]. Biological Roles and Biochemistry of the Lipoxygenase Pathway, Harold W. Gardner.
[3]. Colorimetric Method for the Determination of Lipoxygenase Activity, Gordon E. Anthon and Diane M. Barrett.
[4]. Oxygenation of Unsaturated Fatty Acids by Soybean Lipoxygenase, William L. Smithyand William IC. M. Lands.
[5]. Lipoxygenases: From Isolation to Application, Stefan Hayward, Tertius Cilliers, and Pieter Swart..
- Citation
- Abstract
- Reference
- Full PDF
| Paper Type | : | Research Paper |
| Title | : | Chimera of Heat-labile Enterotoxin B chain conjugate with LipL32 and or LipL21 proteins induces strong reactive antibodies in experimental mice |
| Country | : | Iraq |
| Authors | : | RawahFaraj || Ehsan Abdalla || GopalReddy || Temesgen Samuel || WoubitAbdela |
|
: | 10.9790/264X-0403015868 |
Abstract: Current killed vaccines against Leptospira lack long-term protective ability and are mostly serovar-specific. Hence, there is an urgent need for a vaccine that can provide long-term and broad protection against the many existing Leptospiraserovars. LipL32 and LipL21 are important conserved lipoproteins among pathogenic Leptospira. As a precedent to vaccine development, we amplified and cloned LipL32, LipL21 and heat-labile enterotoxin B subunit (LTB) genes in E. coli by using the Gateway cloning system, followed by recombinant protein expression. The recombinant LipL21 and LipL32 proteins were then chemically conjugated to LTB. Mice were immunized with the LTB-conjugated LipL32 or LipL21 and the antibody responses against the corresponding proteins were compared........
Keywords:Leptospira, Leptospirosis, LipL32, LipL21,Outer membrane protein, Recombinant protein
[1]. Pappas G, Papadimitriou P, Siozopoulou V, Christou L, Akritidis N. The globalization of leptospirosis: worldwide incidence trends. Int J Infect Dis. 2008;12:351-7.
[2]. Levett PN. Leptospirosis. Clin Microbiol Rev. 2001;14:296-326.
[3]. Koizumi N, Watanabe H. Leptospirosis vaccines: past, present, and future. Journal of postgraduate medicine. 2005;51:210-4.
[4]. Branger C, Chatrenet B, Gauvrit A, Aviat F, Aubert A, Bach JM, et al. Protection against Leptospira interrogans sensu lato challenge by DNA immunization with the gene encoding hemolysin-associated protein 1. Infection and immunity. 2005;73:4062-9.
[5]. Bharti AR, Nally JE, Ricaldi JN, Matthias MA, Diaz MM, Lovett MA, et al. Leptospirosis: a zoonotic disease of global importance. The Lancet Infectious diseases. 2003;3:757-71..
- Citation
- Abstract
- Reference
- Full PDF
| Paper Type | : | Research Paper |
| Title | : | Assessing the Biopreservative Potential of Bacteriocin against Some Selected Food Pathogens |
| Country | : | Nigeria |
| Authors | : | Mustapha, Gani || Nafi'u, Abdulkadir || Hizbullahi, M. Usman || Fatima Isah || Fatima I. Jumare |
|
: | 10.9790/264X-0403016973 |
Abstract: Bacteriocins are antimicrobial peptides or proteins ribosomally synthesized by some lactic acid bacteria (LAB). This research study was carried out to assess the potential of bacteriocin from Lactobacillus acidophilus (MS1), Bacillus cereus (MS2) and Staphylococcus epidermidis(MS3) against selected food borne pathogens. The bacteriocin producing bacteria was isolated from animal samples pre-enriched in broth culture of Nutrient agar for 48hrs at 30oC. the biochemical and morphological properties were used to characterize and identify the isolates as Lactobacillus acidophilus, Bacillus cereus and Staphylococcus epidermidis. Crude extract of bacteriocin was obtained by centrifugation of the broth culture (4000r/min) for 20mins. Extract was further purified by precipitation with ammonium.......
Key word: Bacteriocin, Biopreservative, Food pathogens, LAB, Bacillus spp
[1]. Arques JL, Fernandez J, Gaya P, Nunez M, Rodriguez E, Medina M, 2004.Antimicrobial activity of reuterin in combination with nisin against food-borne pathogens. Int J Food Microbiol, 95:225-229.
[2]. Bedford, M. 2000. Removal of antibiotic growth promoters from poultry diets: implications and strategies to minimize subsequent problems. World's Poultry Science Journal 56: 347–365.
[3]. Bouttefroy A, Milliere JB, 2000. Nisin-curvaticin 13 combinations for avoiding the regrowth of bacteriocin resistant cells of Listeria monocytogenes ATCC 15313.Int J Food Microbiol, 62:65-75.
[4]. Cheesbrough, M, 2006. District Laboratory Practice in Tropical Countries. 2nd Edn., Cambridge University Press, Cambridge, UK.
[5]. Cleveland J, Montville TJ, Nes IF, Chikindas ML, 2001. Bacteriocins: safe, natural antimicrobials for food preservation. Int J Food Microbiol, 71:1-20..
- Citation
- Abstract
- Reference
- Full PDF
| Paper Type | : | Research Paper |
| Title | : | Correlation between iron status and thyroid function in beta-thalassemia major of Iraqi patients |
| Country | : | Iraq |
| Authors | : | Shahad FObeid || Sanad B.AL-A'Araji || Bassam FMatti |
|
: | 10.9790/264X-0403017477 |
Abstract: :Iron overload is an important issue in the state of thalassemic patients due to the harmful effect of high concentration of iron deposited in different tissues in the human body including endocrine glands. In the present work, an attempt is carried out to estimate the effect of different levels of iron body status on the function of thyroid glandsin thalassemic major patients in relation to TPO antibodies. One hundred thirty β-thalassemia major patients divided intothree groups; two groups (low iron overload and high iron overload) and sixty-five healthy persons as control groups.Blood samples were taken in the fasting to check laboratory tests such as ferritin, T3, T4, TSH and TPO estimated by ELISA technique and iron status estimated by spectrophotometer technique. 119(61%)of........
Keywords: Beta thalassemia major;Iron overload;Thyroid function
[1]. Delvecchio, m. & cavallo, l. 2010. Growth and endocrine function in thalassemia major in childhood and adolescence. Journal of endocrinological investigation, 33, 61-68.
[2]. Dolai, t. K., baul, s. N., mandal, p. K., de, r. & chakrabarti, p. 2016. A prospective study of thyroid function status in patients of haemoglobin e beta thalassemia and correlation with serum ferritin level. Blood, 128, 4837-4837.
[3]. Drema, l., singh, p., singh, k., singh pannu, m., kaur, m. & neki, n. 2017. Thyroid profile in multi transfused children of beta thalassemia major and its correlation with serum ferritin levels. Int. J. Curr. Res. Med. Sci, 3, 14-21.
[4]. Eshragi, p., tamaddoni, a., zarifi, k., mohammadhasani, a. & aminzadeh, m. 2011. Thyroid function in major thalassemia patients: is it related to height and chelation therapy? Caspian journal of internal medicine, 2, 189-193.
[5]. Hadeed, w. A., alhially, y. A. H. & bashi, a. Y. D. 2015. Comparison of thyroid function tests between splenectomised and non-splenectomised β-thalassemia major patients tikrit journal of pure science 20, 61-66..
- Citation
- Abstract
- Reference
- Full PDF
| Paper Type | : | Research Paper |
| Title | : | Green Nanoparticles: Synthesis and Applications |
| Country | : | India |
| Authors | : | Manish Soni || Priya Mehta || Anjali Soni || Girish K. Goswami |
|
: | 10.9790/264X-0403017883 |
Abstract: The increased use of nanoparticles in biomedical sciences, electronics, and drug delivery has led to development of various methods of synthesizing nanoparticles using physical, chemical and biological methods. But the limitation like toxicity, hazardous chemicals and high cost of production led to develop alternative methods for production of nanoparticles. Green synthesis of nanoparticles is an alternative and emerging area of research. The green synthesis of nanoparticles using microorganisms is a promising approach which is eco friendly and cost effective method.
Keywords: nanoparticles, Green synthesis, Nanotechnology, Microorganisms
[1]. Afifi M., et al. "Ameliorative effect of zinc oxide nanoparticles on antioxidants and sperm characteristics in streptozotocin- induced diabetic rat testes" BioMed Research International (2015): doi: 10.1155/2015/ 153573.
[2]. Agarwal H., et al. "A review on green synthesis of zinc oxide nanoparticles –An eco-friendly approach" Resource-Efficient Technologies 3 (2017): 406–413.
[3]. Arka Dutta Gupta et al. " A Review on Recent Advancement of Cancer Therapy using Nanoparticles " Biochemistry & Molecular Biology Letters Review (2017) 3 (1) 104.
[4]. Birol H., et al. "Preparation of ceramic nanoparticles via cellulose-assisted glycine nitrate process: a review" RSC Adv. 3 (2013): 2873-2884
[5]. Chandrasekaran R., et al. "Formulation of Carica papaya latex-functionalized silver nanoparticles for its improved antibacterial and anticancer applications" Journal of Molecular Liquids 219 (2016): 232–238.
- Citation
- Abstract
- Reference
- Full PDF
| Paper Type | : | Research Paper |
| Title | : | Effect of Ethanolic extract of Neem & Tulsi for repellency and insecticidal activity against the Adult of Tenebrio molitor (Tenebrionidae) |
| Country | : | India |
| Authors | : | S.M. Mahboob Hassan || Pintu Kumar shaw |
|
: | 10.9790/264X-04038487 |
Abstract: Tenebrio molitor Linnaeus (Coleoptera: Tenebrionidae) is a pest of stored products. This insect also infests stored food grains. According to researchers, T. Molitor motives losses up to 15% of grains and flour manufacturing globally. T. Molitor is controlled chiefly with chemical insecticides, but this approach has restrictions toward stored product insects due to residual toxicity and insect resistance. The study aimed to assess the potential of ethanolic extracts of Neem & Tulsi on different concentrations for their repellency and insecticidal activity against T. Molitor Average mortality share indicated that the extracts brought on large mortality and repellency on the treated insect and bioassays additionally indicated that the poisonous and repellent impact used to......
Keywords: Neem & Tulsi, Tenebrio molitor, mortality, repellency
[1]. Abbott WS (1925). A method of computing the effectiveness of an insecticide. J. Econ. Entomol., 18: 266-267.
[2]. Amin MR, Shahjahan M, Eltaj HF, Iqbal TMT, Alamgir M, Hossain (2000). Bangladesh J. Entomol, 10 (1 & 2): 1-13.
[3]. Duncun DB (1957). A significance test for differences between ranked treatments in an analysis of variance. Virgina J. Sci. 2: 171-189.
[4]. Haque (2002). Chemical Methods of Leaf Extraction of Bankalmi, Polygonum hydropiper for Controlling Rice Hispa Beetles, Dicladispa armiger (Olivier) (Coleoptera: Chrysomelidae) in Bangladesh. J. Biol. Sci. 2 (12): 782-784.
[5]. Kabaru JM, Gichia L, (2001). Insecticidal activity of extracts derived from different parts of the mangrove tree rhizophora Mucronata (rhizophoraceae) Lam. against three arthropods; Afr. J. Sci. Tech. (AJST), Sci. & Eng. Series Vol. 2, No. 2, pp. 44-49AJST..
- Citation
- Abstract
- Reference
- Full PDF
| Paper Type | : | Research Paper |
| Title | : | MIS Determination of Etoricoxib used in Pharmaceutical Formulations |
| Country | : | India |
| Authors | : | Abhijeet Kumar Shrivastava || Snigdha Lal |
|
: | 10.9790/264X-04038899 |
Abstract: The present study was undertaken to develop a validated, rapid, simple, and low-cost infra-red (IR) spectrophotometric method for estimating Etoricoxib (ETX) in pharmaceutical formulations. The proposed method was validated as per International Conference on Harmonization (ICH) guidelines including parameters as linearity, accuracy, precision, reproducibility, and specificity. A Solid Inclusion Complex of Etoricoxib with β-Cyclodextrin was prepared and analysed by FTIR-ATR. Linearity range was found to be 2.0 to 16 μg/ml. The results demonstrated that the proposed methods are accurate, precise and reproducible, while being simple, economical and less time consuming than other available methods and can be used for estimation of etoricoxib in different dosage forms. The results obtained were also in comparison with that of UV-spectrophotometric analysis (validation method).
[1]. BC Smith. Introduction to infrared spectroscopy. In: Fundamentals of Fourier TransformInfraredSpectroscopy, 2nd Edn. CRC Press:Boca Raton: 1996; 43–57p.
[2]. HCPSherman.Infraredspectroscopy.In:F.Settle(Ed).HandbookofInstrumentalTechniques for Analytical Chemistry, 4th edn. Separation Sciences Research and ProductDevelopmentMallinckrodt, Inc.: MallinckrodtBaker Division: 1995;251–253p.
[3]. J Mohan. Infrared spectroscopy. In: Organic Spectroscopy – Principles & Applications,2ndedn. Narosa Publishing House, Chennai: 2005; 19–50p.
[4]. DASkoog,JFHoller,SRCrouch.AnIntroductiontoInfraredSpectroscopy.In:InstrumentalAnalysis.Brooks/Cole,Canada:2007;477–527p.
[5]. BHStuart.ExperimentalMethods.In:InfraredSpectroscopy:Fundamentals&Applications,5th edn.; John Wiley:New York: 2004; 23–46p.