Volume-10 ~ Issue-10 ~ October-2017

Abstract: The design and synthesis of the new biologically active binuclear amino acid Schiff base metal complexes. The Schiff base metal complexes were synthesized and characterized using different physicochemical studies as IR spectra, XRD analysis, elemental analyses, mass spectra, conductivity measurement, UV–vis Spectra, 1HNMR spectra and its metal complexes were screened for their antimicrobial activity. Furthermore, IR spectral studies of all the binuclear amino acids Schiff base metal complexes exhibit a similar aspect about the bonding mode of the ligand to the metal ions and reveal that the amino acid Schiff base ligand has coordinated through the deprotonated.........

Keywords: Amino acid Schiff base, antibacterial activity, MCF-7 cancer cell line.

[1]. Ahmed M. Abu-Dief, Ibrahim M.A. Mohamed, A review on versatile applications of transition metal complexes incorporating Schiff bases, Beni – suef university journal of basic and applied sciences, 4, 2015, 119-133.
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[3]. A. Angoso, J. M. Martin-Llorente, J. L. Manzano, M. Martin, R. Martin, E. Rodriguez., Preparation and study of amino acid (DL-leucine, L-isoleucine, L-histidine) Schiff bases with ethyl-α-ketocyclopentylcarboxylate and the corresponding copper(II) complexes, Inorganica Chimica Acta, 195(1), 1992, 45-49.
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Abstract: Background: Lead poisoning is said to be the most common environmental illness of children. The incidence varies with age, socioeconomic status, the population of a given community, race, and the age of the home. Aim: This study is intended to assess lead poisoning among primary School Children in Gezira State and to provide data for assessing the extent and nature of a given community's lead contamination problems. Method: This study was conducted at Gezira State (wad Madni) from primary School Children localized in the main street. A total of 39 samples were collected from three schools (two female schools and one school for male).30 as exposed and 9 as control. Age between 6-14 years old. Blood lead level analysis was carried out by using NIOSH method measured by Atomic absorptionon...............

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Abstract: The synthesis and optical, electrochemical, and electronic properties of N,-(5-amin-1,10-phenanthroline)perylene-3,4,9,10-tetracarboximonoimide [pPDI] are reported. The molecular structure of the compound was elucidated by FTIR, mass spectrometry, elemental analysis (CHN), and DFT calculations. Their optical and electrochemical properties were investigated by absorption and fluorescence spectroscopy and cyclic voltammetry. Spectroscopic and electrochemical studies for pPDI show that phenanthroline coordination does not affect the optical and electrochemical properties of the perylene monoimide ligand.

Keywords:dye,organic synthesis, perylene tetracarboxylic, absorption, luminescence

[1]. M. Cazacu, A. Vlad, A. Airinei, A. Nicolescu & I. Stoica I (2011) New imides based on perylene and siloxane derivatives. Dyes and Pigments 90(2), 2011, 106-113
[2]. S. Asir, A.S; Demir, H. Icil, The synthesis of novel, unsymmetrically substituted, chiral naphthalene and perylene diimides: Photophysical, electrochemical, chiroptical and intramolecular charge transfer properties. Dyes and pigments, 84(1), 2010, 1-13
[3]. E. R. dos Santos, J. Pina, T. Venâncio, C. Serpa, J. M. G. Martinho, R. M. Carlos, Photo-Induced Energy and Electron-Transfer Reactions by Polypyridine Ruthenium (II) Complexes Containing a Derivatized Perylene Diimide, J. Phys. Chem. C, 120, 2016, 22831–22843.
[4]. G. Turkmen, S. Erten-Ela, S. Icli, Highly soluble perylene dyes: Synthesis, photophysical and electrochemical characterizations, Dyes and Pigments, 83, 2009, 297–303
[5]. Z. Yu, Y. Wu, Q. Peng, C. Sun, J. Chen, J. Yao, H. Fu, Accessing the Triplet State in Heavy-Atom-Free Perylene Diimides, Chemistry - A European Journal, 22, 2016, 4717–4722.

Abstract: The investigation on mixed-ligand cyanonitrosyl complexes of chromium in its unusual oxidation state, from-II to +VI among the VI group transition elements. The physico-chemical properties and elucidation of structural aspects of the synthesized compounds have been characterized by different physical methods i.e., conductance, magnetic and Infrared speetral measurement C,H,N and S were estimated microanalytically, chromium estimated as chromic oxide (CrO3). Co-ordination compounds of Uracil and their substituted of CrI are synthesized in this paper.

Keywords: Ligands, Transition elements, Cyanonitrosyl,cromic oxide, Uracil

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Abstract: The reagent 4-Hydroxy benzaldehyde thiosemicarbazone (4-HBTS) has been synthesized and characterized and itsanalytical applications were investigated. The compilexing reagent 4-HBTS reacts with aqueous solution of U (VI) ion in the pH range of 5.0-5.5at room temperature and forms a yellow coloured 1:1 [U(VI):4-HBTS] complex with stability constant 3.74x105. The complex has maximum absorption at 350 nm. The molar absorptivity and sandell'ssensitivity for the coloured solution are found to be 1.1X104 Lmol-1cm-1 and 0.002164 μg cm-2 respectively. Beer's lawis obeyed in the range of 0.9522-9.552 μg/mL. The interference of various diverse ions has been studied.

Keywords: Uranium (VI). 4-Hydroxybenzaldehydethiosemicarbazone, SpectroPhotometry, environmental samples,

[1]. Lutfullah, Farheen Khan, Nafisur Rahman and Syed Najmul Hejaz Hazmi.) Indian Journal of Chemical Technology. 2009, 16, 437-441
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Abstract: Calculations of interaction energy (Eint), charge transfer (ÄN) and lowering of energy (E) between acceptor Chromium halides (Fluride,chloride,bromide and iodide)and donor organic bases (Quinoline,8-nitroquinoline,5-nitroquinoline,8-quinolinesulphonic acid,2-aminoquinoline,2-phenylquinolne,quinolinic acid,isoquinoline) have been done by DFTB88PW91method using CAChe software. The results indicate that acceptor strength of chromium halides with organic basis is in order CrF2> CrCl2 > CrBr2 >CrI2 form stable complexes in most of the cases and the base strength show that the 5-nitroquinoline is the weakest base and 2- phenylquinoline is the strongest base against least of the acceptors. The result obtained by interaction energy,charge transfer and lowering of energy give almost the same result.The value of energy transfer showed that the complex formation capability is in the sequence flouride> chloride> bromide> iodide.

Keywords: DFT method; Interaction energy; Charge transfer; Lowering of energy; Donor; Acceptor.

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Abstract: The present paper is an overview of different methods of synthesis of Schiff bases and their complexes from different set of amino and carbonyl compounds, the applications of Schiff base complexes as antimicrobial, antifungal, antibacterial, antipollutant, anti tumour and anticarcinogenic, which also includes the activity of Schiff base complexes widely utilized to analyze some physical parameters of compounds like pH, electrochemical and thermodynamic studies. Recently these metal complexes are also extensively used in pharmaceutical industry. Therefore the present paper is concerning the different aspect of synthesis and wide scope of application of Schiff base complexes

Keywords: anticarcinogenic, antitumor, pH, electrochemistry, thermodynamics.

[1] El-Bindary, A. Z. El-Sonbati, M. A. Diab, and M. K. Abd El-Kader, "Potentiometric and Thermodynamic Studies of Some Schiff-Base Derivatives of 4-Aminoantipyrine and Their Metal Complexes" Journal of Chemistry Volume 2013 (2013), Article ID 682186, 6 pages

[2] Ahlam Jameel Abdulghani*, Rasha Khuder Hussain "Synthesis and Characterization of Schiff BaseMetal Complexes Derived from Cefotaximewith 1H-indole-2,3-dione (Isatin) and 4-N,N-dimethyl-aminobenzaldehyde" Open Journal of Inorganic Chemistry, 2015, 5, 83-101

[3] A.P. Mishra, Krishna Kumar & L.R. Pandey, "Synthesis and antimicrobial studies of Co(II),Ni(II) and Cu(II) complexes with schiff bases" J.lnd. Chem.,2006. Soc, Vol. 83 January, 2006.

[4] Abdou Saad , 1 , * Moshira Mohamed Abd El-Waheed, 2 Mohammed Ahmed Wahba, 3 and Nahla Abd El-Halim Abou El-Fadl 1 "Synthesis, Characterization, and Anticancer Activity of New Metal Complexes Derived from 2-Hydroxy-3-(hydroxyimino)-4-oxopentan-2-ylidene)benzohydrazide" Bioinorg Chem Appl. 2015; 2015: 126023

[5] Asadi M1, Torabi S2, Mohammadi "Synthesis, characterization, and thermodynamics of some new unsymmetrical Schiff bases of salicylaldehyde with 3,4-diaminopyridine and their cobalt(III) complexes" S K3.2014 Mar 25;122:676-81. Epub 2013 Oct 9..

Abstract: The extraction behaviour of La(III) with Tri-n-octylamine in Kerosene has been studied through a novel method solvent extraction. The mechanism of extraction and the species extracted have been identified. Quantitative extraction of La(III) with TOA was achieved in Kerosene by changing different parameters such as acid variation, diluent effect, metal concentration variation, extractant variation and effect of chloride ion concentration on extraction of La (III) were studied. The percentage of La (III) became 42.4% with 0.1M TOA from 1M nitric acid. Chloroform was found to be effective diluent for the extraction of La(III) with TOA.

Keywords: lanthanum; solvent extraction; nitric acid; tri-octyl amine; kerosene.

[1] D. H. Cheng, X. W. Chen, Y. Shu and J. H. Wang, "Se- lective Extraction/Isolation of Hemoglobin with Ionic Liquid 1-Butyl-3-trimethylsilylimidazolium Hexafluoro- phosphate (BtmsimPF6)," Talanta, . 75(2008), No. 5, pp. 1270-1278. doi:10.1016/j.talanta.2008.01.044
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Abstract: The main source of edible oil are Soybean, Sunflower and Rice bran. The crude oil is then refined in order to remove free fatty acid and other triacyl glyceride. The refining of crude oil generates large amount of waste water. The use of H2SO4 generates highly acidic water with heavy load of organic matter, COD etc. This waste water is then treated in effluent treatment plant by physical and chemical process. The organic contamination decreases but hardness increases due to use of calcium chloride and alum. This also increases the chloride ion concentration hence the effluent coming out after secondary treatment is also unfit for reuse or recycle and further treatment is required before it is discharged or reused.

Keywords: Soybean, Rice Bran Oil, ETP, COD, BOD..

[1] Sandile P Makhize and Faizal Bux Assessment of activated sludge to emediate edible oil effluent South African Journal of Science 2001 Vol. 97 PP 380-382.
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Abstract: The present study is aimed at exploring the spectral and antimicrobial properties of oil extracted from the seeds of alligator pepper (Aframomum melegueta). The spectral properties (FTIR, 1H, 13C and DEPT-135 NMR) of the oven dried and stripped oil extracted from seeds of alligator pepper seeds werestudied. The FTIR, 1H, 13C and DEPT-135 NMR spectra indicates that the major constituents of the oil were triacyl glycerols (TAGS) containing unsaturated acyl chains. Prominent peaks in the FTIR include: 3517.98 (carbonyl overtone), 2924.49(CH), 1748.50 (C-O of carbonyl ester) and 1604.54 (C-C cis). The major signals in the proton NMR spectrum were observed between 0.80 and 5.5 ppm. The signals...............

Keywords:Alligator pepper oil, Antimicrobial, FTIR, 1H, 13C NMR Spectra..

[1]. Adeyeye E.I., Adesina, A.J. & Fagbohun, E.D.(2014): Lipid Composition of Aframomum melegueta, Zingiber officinale, and Xylopicaethiopica. BioMed Research (Food &Nutrition Research. 1(1) :1-16.
[2]. Alaje D.O., Owolabi K.T., Olakunle T.P., Oluoti O.J., & Adetuberu I.A. (2014):
[3]. Nutritional, Minerals and Phytochemicals composition of Garcinia cola [Bitter cola] and Aframomum melegueta [Alligator pepper]. IOSR Journal of Environmental Science, Toxicology and Food Technology (IOSR-JESTFT) 8 (1) 86-91.
[4]. Angaye, S.S., Fekarurhobo, G.K and Obomanu, F.G (2013): Photosensitized oxidation of the African pear pulp oil. Australia Journal of Basic and Applied Sciences.7(8) 194-201.
[5]. Bounatirou, S., Smiti S., Miguel, M.G., Faleiro. L., Rejeb, M.N., Neffati, M., Costa, M.M. Figueiredo, A.C., Barroso, J.G.,& Pedro, L.G. (2007): Chemical composition, antioxidant and antimicrobial activities of the essential oils isolated from Tunisian Thymus capitus

Abstract: Ionophoretic technique is studied as a novel tool for the study of binary metal complexes of Cobalt (II)-ADP and Cobalt (II)-ATP. The stability constants of Cobalt (II)-ADP and Cobalt (II)-ATP Complexes equilibria in simple and mixed ligand systems in solutions. Are found to be 104.68and 105.50 respectively. These values are determined at 250C and at ionic strength equal to 0.1M (NaClO4). The specially designed electrophoretic tube (1) has been used for investigation of these complexes in the solution.

Keywords: Ionophoretic technique, Electrophoretic tube, Stability, ADP, ATP, nucleotides

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Abstract: This study was aimed at synthesizing, characterizing and evaluating the antifungal activity of the Schiff base and Cu (II) complex. The reaction of the mixture of ethanol solution of acetylacetone and leucine yielded a Schiff base. The interaction between the Schiff base in hot aqueous methanol mixture and cobalt (II) chloride in ethanol gave the cobalt (II) Schiff base complex. The complex was characterized by decomposition/melting point temperatures, solubility test, IR spectrophotometry, colour determination, dissociation constant of Schiff base and antifungal activity. The Schiff base obtained has yellow colour, with a melting point of 250oC and percentage yield of 54.67% while the cobalt (II) complex obtained had a purple colour with decomposition temperature of 174oC and percentage yield of 80.64%.................

Keywords: Antifungal, Acetylacetone, Cobalt (II), Leucine, Schiff base

[1] ZH Chohan, M Arif, ZH Akhtar and ST Claudiu. Synthesis, Characterization and Antimicrobial activity of Cobalt metal complex
against multi-resistant bacterial and fungal pathogens. Bioinorganic Chemistry and Applications Journal, 2(6), 2006, 1-13.
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Journal of Chemical Education, 88(10), 2011, 1444-1445.
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Abstract: A Baseline blood concentration of metals is an important indication of observing metals exposure in environmental and occupational settings. On this regard, a study was conducted on 116 men and 84 women 20-65 years of age in Libya. Its aim was to determine the blood plasma levels of manganese for those who live in the inner city of Tripoli. Blood plasma samples were extracted from 200 participants between April and July 2013.Manganeselevels in blood plasma were determined using Graphite Furnace Atomic Absorption Spectrometry (GFAAS). There was significant age-related correlation in blood plasma levels of manganese which correlated positively with age (P for trend = 0.05). The mean (SD) of manganese was 2.14 μg/l (0.37) with a peak value reached 3.02 μg/l.

Keywords: Manganese, blood plasma, GFAAS, Tripoli region, Libya

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Abstract: Sterculia urens belongs to family Malvaceae. The tree is highly valued ethano botanically .A large number of compounds have been isolated from fruits ,stem and bark of the plant .In the present investigation ,chemical investigation of seeds has been taken up.

Keywords: Ethano botany, medicinal uses, Seeds

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